Evidence map›Paper›PMID 33132641›Full record

ArticleWorld journal of gastroenterology2020

Monitoring hepatitis C virus treatment rates in an Opioid Treatment Program: A longitudinal study.

Arantza Sanvisens, Inmaculada Rivas, Eva Faure, Néstor Espinach, Anna Hernandez-Rubio, Xavier Majó, Joan Colom, Robert Muga

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Arantza SanvisensDepartment of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Badalona 08916, Spain.
Inmaculada RivasMental Health and Addiction Service, Badalona Serveis Assistencials-BSA, Badalona 08911, Spain.
Eva FaureMental Health and Addiction Service, Badalona Serveis Assistencials-BSA, Badalona 08911, Spain.
Néstor EspinachMental Health and Addiction Service, Badalona Serveis Assistencials-BSA, Badalona 08911, Spain.
Anna Hernandez-RubioDepartment of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona 08916, Spain.
Xavier MajóProgram on HIV, STIs and Viral Hepatitis - PCAVIHV Public Health Agency of Catalonia, Generalitat de Catalunya, Barcelona 08005, Spain.
Joan ColomProgram on HIV, STIs and Viral Hepatitis - PCAVIHV Public Health Agency of Catalonia, Generalitat de Catalunya, Barcelona 08005, Spain.
Robert MugaDepartment of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona 08916, Spain. rmuga.germanstrias@gencat.cat.
Instituto de Salud Carlos III · ESHospital Universitari Germans Trias i Pujol · ESUniversitat Autònoma de Barcelona · ESGovernment of Catalonia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDirect-acting antivirals (DAAs) are recommended for the treatment of hepatitis C virus (HCV) infection in patients treated with methadone or buprenorphine.

aimTo assess HCV treatment rates in an Opioid Treatment Program (OTP).

methodsThis longitudinal study included 501 patients (81.4% men, median age: 45 years; interquartile range: 39-50 years) enrolled in an OTP between October 2015 and September 2017. Patients were followed until September 2019. Data on socio-demographics, substance use, HCV infection, human immunodeficiency virus (HIV) infection and laboratory parameters were collected at entry. We analyzed medical records to evaluate HCV treatment. Kaplan-Meier methods and Cox regression models were used to analyze the DAA treatment uptake and to identify treatment predictors.

resultsPrevalence of HCV and HIV infection was 70% and 34%, respectively. Among anti-HCV-positive (

conclusionHCV treatment is evolving in patients with HCV-HIV co-infection. Ongoing drug use while in an OTP might negatively impact the readiness to treat infection.

Indexed as

CoinfectionHepatitis CHepatitis C, ChronicHIV InfectionsAdultAnalgesics, OpioidAntiviral AgentsFemaleHepacivirusHumansLongitudinal StudiesMaleMiddle AgedAnalgesics, OpioidAntiviral AgentsDirect-acting antiviral agentsDrug useHepatitis C virus infectionHuman immunodeficiency virus infectionOpioid agonist therapyOpioid Treatment Program

Identifiers

PMID33132641
PMCPMC7579757
OpenAlexW3096001341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.