Evidence map›Paper›PMID 33132579›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2020

Hypocalcemic Seizure Due to Vitamin D Deficiency.

Robin G Manappallil, Raghuram Krishnan, Pradeep P Veetil, Harilal Nambiar, Ummer Karadan, Revathy Anil, Blessy Josephine

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Vitamin D deficiency presenting as seizures.Medical journal, Armed Forces India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Robin G ManappallilDepartment of Internal Medicine, Baby Memorial Hospital, Kozhikode, Kerala, India.
Raghuram KrishnanDepartment of Cardiology, Baby Memorial Hospital, Kozhikode, Kerala, India.
Pradeep P VeetilDepartment of Endocrine Surgery, Baby Memorial Hospital, Kozhikode, Kerala, India.
Harilal NambiarDepartment of Cardiothoracic and Vascular Surgery, Baby Memorial Hospital, Kozhikode, Kerala, India.
Ummer KaradanDepartment of Neurology, Baby Memorial Hospital, Kozhikode, Kerala, India.
Revathy AnilDepartment of Internal Medicine, Baby Memorial Hospital, Kozhikode, Kerala, India.
Blessy JosephineDepartment of Internal Medicine, Baby Memorial Hospital, Kozhikode, Kerala, India.
Baby Memorial Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo emphasize the importance of vitamin D supplementation.

backgroundThe incidence of vitamin D deficiency has been increasing worldwide, probably due to decreased exposure to sunlight and unbalanced diet. Severe hypocalcemia following vitamin D deficiency is rather uncommon, and this leading to seizures in adults is a rare scenario. CASE DESCRIPTION: This is the case of a 70-year-old female, a known case of coronary artery disease, who presented with one episode of seizure. Computed tomography of her brain revealed diffuse age-related atrophic changes, and electroencephalogram showed diffuse cerebral dysfunction. She was found to have severe hypocalcemia with secondary hyperparathyroidism due to vitamin D deficiency. Vitamin D bolus was given along with calcium correction, following which she improved.

conclusionThere are a few reports of hypocalcemic seizures among children; however, the incidence is rare among adults. Calcium and vitamin D supplementation forms the mainstay of treatment. CLINICAL SIGNIFICANCE: Hypocalcemic seizure is uncommon, especially among adults. Vitamin D deficiency resulting in hypocalcemic seizure, to the best of our knowledge, is an unreported scenario. This case highlights the importance of vitamin D supplementation in those with reduced sunlight exposure. HOW TO CITE THIS ARTICLE: Manappallil RG, Krishnan R, Veetil PP, Nambiar H, Karadan U, Anil R,

Indexed as

CalciumHyperparathyroidismHypocalcemiaSeizureVitamin D

Identifiers

PMID33132579
PMCPMC7584818
OpenAlexW3091875860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.