Evidence map›Paper›PMID 33132430›Full record

Observational studyNagoya journal of medical science2020

Clinical outcomes of neoadjuvant chemotherapy for patients with breast cancer: Tri-weekly nanoparticle albumin-bound paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide: a retrospective observational study.

Masato Shizuku, Masahiro Shibata, Yoshimi Shimizu, Dai Takeuchi, Yutaka Mizuno

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Nagoya journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Current oncology (Toronto, Ont.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Masato ShizukuDepartment of Breast Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.
Masahiro ShibataDepartment of Breast Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.
Yoshimi ShimizuDepartment of Breast Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.
Dai TakeuchiDepartment of Breast Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.
Yutaka MizunoDepartment of Breast Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.
Yokkaichi Municipal Hospital · JPNagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoadjuvant chemotherapy (NAC) using the combination of anthracycline and taxanes is the standard regimen for patients with primary breast cancer. Among the taxanes, conventional paclitaxel (PTX) and docetaxel have usually been adopted in the neoadjuvant or adjuvant setting. Nanoparticle albumin-bound paclitaxel (nab-PTX) is a solvent-free formulation that can be delivered to cancer cells at higher doses than conventional PTX. This study is a retrospective observational study in a single institution. We evaluated the efficacy and safety of nab-PTX followed by 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) in the neoadjuvant setting. In this study, 50 patients with primary breast cancer received nab-PTX (q3w, 260 mg/m

Indexed as

AdultAgedAlbumin-Bound PaclitaxelBreast NeoplasmsCyclophosphamideEpirubicinFemaleFluorouracilHumansMiddle AgedPaclitaxelPilot ProjectsRetrospective StudiesTrastuzumabAlbumin-Bound PaclitaxelCyclophosphamideEpirubicinFluorouracilPaclitaxelTrastuzumabbreast cancerFECnab-PTXneoadjuvant chemotherapy

Identifiers

PMID33132430
PMCPMC7548255
OpenAlexW3094721456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.