Evidence map›Paper›PMID 33132014›Full record

ArticleJournal of the American Medical Directors Association2021

Machine Learning Algorithms to Predict Mortality and Allocate Palliative Care for Older Patients With Hip Fracture.

Michael P Cary, Farica Zhuang, Rachel Lea Draelos, Wei Pan, Sathya Amarasekara, Brian J Douthit, Yunah Kang, Cathleen S Colón-Emeric

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  15. Development and reporting of artificial intelligence in osteoporosis management.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michael P CarySchool of Nursing, Duke University, Durham, NC, USA; Center for the Study of Aging and Human Development, Duke University, Durham, NC, USA. Electronic address: michael.cary@duke.edu.
Farica ZhuangDepartment of Computer Science, Duke University, Durham, NC, USA.
Rachel Lea DraelosDepartment of Computer Science, Duke University, Durham, NC, USA; School of Medicine, Duke University, Durham, NC, USA.
Wei PanSchool of Nursing, Duke University, Durham, NC, USA.
Sathya AmarasekaraSchool of Nursing, Duke University, Durham, NC, USA.
Brian J DouthitSchool of Nursing, Duke University, Durham, NC, USA.
Yunah KangSchool of Nursing, Duke University, Durham, NC, USA.
Cathleen S Colón-EmericCenter for the Study of Aging and Human Development, Duke University, Durham, NC, USA; School of Medicine, Duke University, Durham, NC, USA; Geriatric Research, Education and Clinical Center, Durham Veterans Affairs Medical Center, Durham, NC, USA.
Duke University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
Institutional Career Development CoreKL2TR002554 · NCATS · DUKE UNIVERSITY · PI SVETKEY, LAURA P · 2018 to 2022
$8.2M
Mentoring Intervention Development in Fall and Fracture PreventionK24AG049077 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2015 to 2019
$361k
NCATS NIH HHS KL2 TR002554NIA NIH HHS K24 AG049077NIA NIH HHS P30 AG028716NIGMS NIH HHS T32 GM007171
6 · The paper itself

Abstract

objectivesTo evaluate a machine learning model designed to predict mortality for Medicare beneficiaries aged >65 years treated for hip fracture in Inpatient Rehabilitation Facilities (IRFs).

designRetrospective design/cohort analysis of Centers for Medicare & Medicaid Services Inpatient Rehabilitation Facility-Patient Assessment Instrument data. SETTING AND

participantsA total of 17,140 persons admitted to Medicare-certified IRFs in 2015 following hospitalization for hip fracture. MEASURES: Patient characteristics include sociodemographic (age, gender, race, and social support) and clinical factors (functional status at admission, chronic conditions) and IRF length of stay. Outcomes were 30-day and 1-year all-cause mortality. We trained and evaluated 2 classification models, logistic regression and a multilayer perceptron (MLP), to predict the probability of 30-day and 1-year mortality and evaluated the calibration, discrimination, and precision of the models.

resultsFor 30-day mortality, MLP performed well [acc = 0.74, area under the receiver operating characteristic curve (AUROC) = 0.76, avg prec = 0.10, slope = 1.14] as did logistic regression (acc = 0.78, AUROC = 0.76, avg prec = 0.09, slope = 1.20). For 1-year mortality, the performances were similar for both MLP (acc = 0.68, AUROC = 0.75, avg prec = 0.32, slope = 0.96) and logistic regression (acc = 0.68, AUROC = 0.75, avg prec = 0.32, slope = 0.95). CONCLUSION AND IMPLICATIONS: A scoring system based on logistic regression may be more feasible to run in current electronic medical records. But MLP models may reduce cognitive burden and increase ability to calibrate to local data, yielding clinical specificity in mortality prediction so that palliative care resources may be allocated more effectively.

Indexed as

Palliative CareRehabilitation CentersAgedAlgorithmsHumansMachine LearningMedicareRetrospective StudiesUnited StatesFunctional statuship fractureinpatient rehabilitation facilitiesmortality

Identifiers

PMID33132014
PMCPMC7867606
OpenAlexW3097523282

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.