Evidence map›Paper›PMID 33131423›Full record

ArticleRNA biology2021

Structure of

Ritwika Basu, Catherine D Eichhorn, Ryan Cheng, Robert D Peterson, Juli Feigon

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Progress in 7SK ribonucleoprotein structural biology.Frontiers in molecular biosciences · 2023
    Review
  7. Telomerase structural biology comes of age.Current opinion in structural biology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ritwika BasuDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.
Catherine D EichhornDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.ORCID 0000-0001-8624-1961
Ryan ChengDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.
Robert D PetersonDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.
Juli FeigonDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

Y-FAMILY POLYMERASES AND CO-FACTORS IN TRANSLESION REPLICATIONP41RR015301 · NCRR · CORNELL UNIVERSITY ITHACA · PI DONG, ZIGANG · 2001 to 2011
$28.2M
Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Structural biology of telomerase and telomeresR35GM131901 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JULI FEIGON · 2019 to 2026
$5.7M
800 MHz NMR Console and Cryoprobe ReplacementS10OD025073 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FEIGON, JULI · 2018 to 2018
$1.1M
Bruker Avance III Console and QCI Cryoprobe for a 600 MHz NMR SpectrometerS10OD016336 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CLUBB, ROBERT THOMPSON · 2014 to 2014
$600k
NCRR NIH HHS P41 RR015301NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R35 GM131901NIH HHS S10 OD016336NIH HHS S10 OD025073
6 · The paper itself

Abstract

La-related proteins 7 (LARP7) are a class of RNA chaperones that bind the 3' ends of RNA and are constitutively associated with their specific target RNAs. In metazoa, Larp7 binds to the long non-coding 7SK RNA as a core component of the 7SK RNP, a major regulator of eukaryotic transcription. In the ciliate

Indexed as

Amino Acid SequenceBinding SitesCloning, MolecularConserved SequenceCrystallography, X-RayEscherichia coliGene ExpressionGenetic VectorsHumansModels, MolecularProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Interaction Domains and MotifsRecombinant ProteinsRibonucleoproteinsLarp7 protein, humanpof8 protein, S pombeRecombinant ProteinsRibonucleoproteinsRNARNA Recognition Motif ProteinsSchizosaccharomyces pombe Proteins7SKLa proteinLARPNMRRNARRMtelomeraseX-ray crystallographyxRRM

Identifiers

PMID33131423
PMCPMC8244769
OpenAlexW3095495941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.