Evidence map›Paper›PMID 33130973›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2021

The potential role of nontyphoidal salmonellosis in gastric cancer: a nationwide matched cohort study.

Renin Chang, James Cheng-Chung Wei, Mei-Chen Lin, Yao-Min Hung

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. NontyphoidalInternational journal of environmental research and public health · 2022
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Renin ChangDepartment of Emergency Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
James Cheng-Chung WeiDivision of Allergy, Immunology and Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan.
Mei-Chen LinManagement Office for Health Data, China Medical University Hospital, Taichung, 40447, Taiwan.
Yao-Min HungDepartment of Internal Medicine, Kaohsiung Municipal United Hospital, 976, Jhong-hua 1st Rd, Gu-shan Dist., Kaohsiung, 80457, Taiwan. ymhung1@gmail.com.
China Medical University · TWI-Shou University · TWKaohsiung Municipal Hsiao-Kang Hospital · TW

Funding

Ministry of Health and Welfare MOHW108-TDU-B-212-133004
6 · The paper itself

Abstract

backgroundThe research is to explore the association between nontyphoidal salmonellosis (NTS) and subsequent gastric cancer.

methodsWe conducted a retrospective study by analyzing hospitalization dataset from the National Health Insurance Research Database in Taiwan. Patients aged 20 years and older with NTS (n = 9 097) admitted between January 1, 2000, and December 31, 2012, were enrolled and followed up until December 31, 2013. The primary outcome was the incidence of gastric cancer. Cox proportional hazards regression was used to estimate the risk of malignancy, accounting for the competing risk of death. In addition, we conducted a sensitivity analysis by propensity score matching and exclusion of malignancy within 1 year observation to minimize measurable confounding and protopathic bias. Negative controls were applied to examine the presence of possible unmeasured confounders in the study.

resultsThe study included 18 194 patients (9097 in each NTS and non-NTS group). The median follow-up time was 7 years. The incidence density rate of gastric cancer was 0.72 per 1000 person-years for the NTS group and 0.40 per 1000 person-years for the non-NTS group. The NTS group had a modestly higher risk of gastric cancer (aHR, 2.02; 95% CI 1.18-3.45) than the non-NTS group. The sensitivity analyses revealed consistent results.

conclusionsPatients with NTS are associated with increased risk of subsequent gastric cancer compared with non-NTS patients. Future research is needed to examine whether NTS is parallel, reactive or causative to gastric cancer.

Indexed as

SalmonellaAdultAgedDatabases, FactualFemaleHumansIncidenceMaleMiddle AgedPropensity ScoreRetrospective StudiesSalmonella InfectionsStomach NeoplasmsTaiwanYoung AdultCohortGastric cancerNontyphoidal salmonellosis

Identifiers

PMID33130973
OpenAlexW3097512761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.