Evidence map›Paper›PMID 33130939›Full record

ArticleCurrent genetics2021

The ASK1 gene regulates the sensitivity of Fusarium graminearum to carbendazim, conidiation and sexual production by combining with β

Xiu-Shi Song, Xue-Mei Xiao, Kai-Xin Gu, Jing Gao, Shao-Chen Ding, Ming-Guo Zhou

Abstract read
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In one paragraph

Article in Current genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiu-Shi SongKey Laboratory of Pesticides, College of Plant Protection, Nanjing Agricultural University, Jiangsu Province, Nanjing, 210095, China.ORCID http://orcid.org/0000-0003-4043-3102
Xue-Mei XiaoKey Laboratory of Pesticides, College of Plant Protection, Nanjing Agricultural University, Jiangsu Province, Nanjing, 210095, China.
Kai-Xin GuKey Laboratory of Pesticides, College of Plant Protection, Nanjing Agricultural University, Jiangsu Province, Nanjing, 210095, China.
Jing GaoKey Laboratory of Pesticides, College of Plant Protection, Nanjing Agricultural University, Jiangsu Province, Nanjing, 210095, China.
Shao-Chen DingKey Laboratory of Pesticides, College of Plant Protection, Nanjing Agricultural University, Jiangsu Province, Nanjing, 210095, China.
Ming-Guo ZhouKey Laboratory of Pesticides, College of Plant Protection, Nanjing Agricultural University, Jiangsu Province, Nanjing, 210095, China. mgzhou@njau.edu.cn.
Nanjing Agricultural University · CN

Funding

National Natural Science Foundation of China 31730072
6 · The paper itself

Abstract

β-tubulin, a component of microtubules, is involved in a wide variety of roles in cell shape, motility, intracellular trafficking and regulating intracellular metabolism. It has been an important fungicide target to control plant pathogen, for example, Fusarium. However, the regulation of fungicide sensitivity by β-tubulin-interacting proteins is still unclear. Here, ASK1 was identified as a β-tubulin interacting protein. The ASK1 regulated the sensitivity of Fusarium to carbendazim (a benzimidazole carbamate fungicide), and multiple cellular processes, such as chromatin separation, conidiation and sexual production. Further, we found the point mutations at 50th and 198th of β

Indexed as

BenzimidazolesCarbamatesDrug Resistance, FungalFusariumMAP Kinase Kinase Kinase 5Plant DiseasesPoint MutationProtein Interaction MapsTubulinBenzimidazolesCarbamatescarbendazimMAP Kinase Kinase Kinase 5TubulinASK1CarbendazimFusariumβ-tubulin

Identifiers

PMID33130939
OpenAlexW3096531147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.