ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2021
Bleeding risk of haemodialysis and peritoneal dialysis patients.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Peritoneal dialysis versus haemodialysis for people commencing dialysis.The Cochrane database of systematic reviews · 2024Pooled it
- Anticoagulation for people receiving long-term haemodialysis.The Cochrane database of systematic reviews · 2024Pooled it
- Comparative iron management in hemodialysis and peritoneal dialysis patients: a systematic review.Frontiers in nephrology · 2024Pooled it
- The use of non-vitamin K oral anticoagulants in dialysis patients-A systematic review.Seminars in dialysis · 2022Pooled it
- Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Review
- Dialysis-Associated Acquired Cystic Kidney Disease as a Cause of Progressive Renal Hemorrhage in a Patient Receiving Hemodialysis: A Case Report.The American journal of case reports · 2026Article
- Predictors and Outcomes of Nonvariceal Upper Gastrointestinal Bleed After Coronary Artery Bypass Grafting: A Nationwide Analysis.Journal of the American Heart Association · 2026Article
- Multinational Real-World Practice Patterns in the Use of Antithrombotic Therapy Among Patients on Hemodialysis and Peritoneal Dialysis.Kidney medicine · 2026Article
- Article
- All-Cause Mortality and Bleeding Risks Associated With Serotonin Reuptake Inhibitors in Patients With End-Stage Kidney Disease and Depression: A Nationwide Cohort Study.Psychiatry investigation · 2025Article
- Long-Term Outcomes and Predictors in Cancer-Related Stroke Using the Linked Data Set.Journal of the American Heart Association · 2025Article
- Association Between the Vascular Ageing of the Carotid Arteries and Different Dialysis Modalities.Cureus · 2025Article
- Clinical Outcomes of Carotid Artery Stenting for Carotid Artery Stenosis in Maintenance Hemodialysis Patients.Neurologia medico-chirurgica · 2025Article
- Cardiovascular and renal comorbidities among saudi patients with type 2 diabetes: A cross-sectional observational study.PloS one · 2025Observational
- Prediction of gastrointestinal bleeding hospitalization risk in hemodialysis using machine learning.BMC nephrology · 2024Article
- Major Bleeding Rates in an International Cohort of Patients With End-Stage Kidney Disease.Kidney international reports · 2024Article
- Hallmarks for Thrombotic and Hemorrhagic Risks in Chronic Kidney Disease Patients.International journal of molecular sciences · 2024Review
- Impact of Dialysis Method on Colon Postpolypectomy Bleeding in Patients with End-stage Renal Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024Article
- Review
- The Safety and Effectiveness of Apixaban in Patients with End-Stage Kidney Disease on Dialysis: A Retrospective Observational Study.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDialysis patients have an increased bleeding risk as compared with the general population. However, there is limited information whether bleeding risks are different for patients treated with haemodialysis (HD) or peritoneal dialysis (PD). From a clinical point of view, this information could influence therapy choice. Therefore the aim of this study was to investigate the association between dialysis modality and bleeding risk.
methodsIncident dialysis patients from the Netherlands Cooperative Study on the Adequacy of Dialysis were prospectively followed for major bleeding events over 3 years. Hazard ratios with 95% confidence intervals (CIs) were calculated for HD compared with PD using a time-dependent Cox regression analysis, with updates on dialysis modality.
resultsIn total, 1745 patients started dialysis, of whom 1211 (69.4%) received HD and 534 (30.6%) PD. The bleeding rate was 60.8/1000 person-years for HD patients and 34.6/1000 person-years for PD patients. The time-dependent Cox regression analysis showed that after adjustment for age, sex, primary kidney disease, prior bleeding, cardiovascular disease, antiplatelet drug use, vitamin K antagonist use, erythropoietin use, arterial hypertension, residual glomerular filtratin rate, haemoglobin and albumin levels, bleeding risk for HD patients compared with PD increased 1.5-fold (95% CI 1.0-2.2).
conclusionsIn this large prospective cohort of incident dialysis patients, HD patients had an increased bleeding risk compared with PD patients. In particular, HD patients with a history of prior bleeding had an increased bleeding risk.
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