ReviewBreast (Edinburgh, Scotland)2020
Occult breast cancer: Where are we at?
Review in Breast (Edinburgh, Scotland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Best treatment options for occult breast cancer: A meta-analysis.Frontiers in oncology · 2023Pooled it
- Regional lymphadenopathy following COVID-19 vaccination: Literature review and considerations for patient management in breast cancer care.European journal of cancer (Oxford, England : 1990) · 2021Pooled it
- Is Mastectomy Necessary in Patients with Occult Breast Cancer and Advanced (N2/N3) Nodal Disease?Annals of surgical oncology · 2026Observational
- Occult breast cancer showing a marked response to pembrolizumab plus gemcitabine and carboplatin therapy complicated by immune-related colitis: A case report.Molecular and clinical oncology · 2026Article
- Occult Breast Carcinoma: Pathologic Features of an Uncommon Clinical Presentation in a Large Cohort.The American journal of surgical pathology · 2026Article
- Clipped Node Pathology as a Guide for Limited Axillary Surgery in Occult Breast Cancer.Annals of surgery · 2026Article
- Case Report: A rare triad of neoplasms: navigating synchronous accessory breast cancer, papillary thyroid carcinoma, and inflammatory nasal papilloma.Frontiers in medicine · 2026Article
- Case Report: Interpectoral lymph node metastasis as an indicator of occult breast cancer: a case of double primary malignancy.Frontiers in oncology · 2026Article
- B cell-mediated immune surveillance defines the favorable prognosis of occult breast cancer: a multi-omics study.Frontiers in immunology · 2026Article
- Symptomatic bone marrow involvement by metastatic occult HR+/HER2- breast cancer treated with ribociclib and letrozole: A case report.Radiology case reports · 2026Article
- A gastric and pleural metastasis of occult breast lobular cancer in an elderly female and radiomics assisted analysis of a rare metastasis.Frontiers in oncology · 2026Article
- Article
- Occult lobular breast carcinoma presenting as bilateral ovarian masses: A case report.International journal of surgery case reports · 2025Article
- Clinical application of 90-gene expression test in a patient with occult breast cancer: a case report and literature review.Breast cancer (Tokyo, Japan) · 2025Review
- Occult Breast Cancer Initially Presenting with Axillary Lymph Node Metastasis: A Case Report.Journal of the Korean Society of Radiology · 2025Article
- Wearable device for axillary lymph node screening in breast cancer based on infrared thermography and artificial intelligence.Breast cancer research : BCR · 2025Article
- Breast cancer: pathogenesis and treatments.Signal transduction and targeted therapy · 2025Review
- Occult breast cancer in an older woman: A case report.Experimental and therapeutic medicine · 2025Article
- Successful Management of Occult Breast Cancer with a Background of Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Interstitial Pneumonia: A Case Report.Surgical case reports · 2025Article
- Occult Breast Cancer Diagnosed from a Solitary Scalp Metastasis without Axillary Lymph Node Involvement: A Case Report.Surgical case reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Occult breast cancer (OBC) is described as an axillary metastatic carcinoma without detection of a primary breast lesion and is uncommon. Significant advances in breast imaging have occurred since its description, decreasing its incidence. However current management is based upon old studies, with variable clinical, radiological and pathological definitions of OBC. We suggest standardised definitions of OBC to facilitate more homogenous data representation in the literature. This review also discusses the conflicting heterogeneous data and its influence in determining the current management guidelines. We discuss whether the current significant surgical recommendations are necessary and postulate whether they could be safely substituted with less invasive management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.