ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2020
Effects of depth electrode montage and single-pulse electrical stimulation sites on neuronal responses and effective connectivity.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Methodologies to detect cortico-cortical evoked potentials: a systematic review.Frontiers in human neuroscience · 2025Pooled it
- EEG CONNECT: A proposed reporting checklist for EEG-based connectivity studies in clinical epilepsy research.Epilepsia open · 2026Review
- Optimization of cortico-cortical spectral response analysis parameters for seizure onset zone localization.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Article
- Effective connectivity between homologous cortices mediated by the corpus callosum: An axono-cortical evoked potentials study.Clinical neurophysiology practice · 2026Article
- Exploring synergies: Advancing neuroscience with machine learning.Signal processing · 2026Article
- Internal and External Validation of Comprehensive High-Frequency Activity Biomarkers for Epilepsy Surgery.medRxiv : the preprint server for health sciences · 2025Article
- Structural and effective brain connectivity in focal epilepsy.Neuroimage. Reports · 2025Article
- Article
- Single pulse electrical stimulation of the medial thalamic surface induces narrower high gamma band activities in the sensorimotor cortex.Scientific reports · 2025Article
- Bipolar and Laplacian montages are suitable for high-gamma modulation language mapping with stereoelectroencephalography.Frontiers in neurology · 2024Article
- Stimulation to probe, excite, and inhibit the epileptic brain.Epilepsia · 2023Article
- Quantitative approaches to guide epilepsy surgery from intracranial EEG.Brain : a journal of neurology · 2023Article
- Cortico-cortical evoked potentials in response to varying stimulation intensity improves seizure localization.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Article
- Stimulating native seizures with neural resonance: a new approach to localize the seizure onset zone.Brain : a journal of neurology · 2022Article
- Six-dimensional dynamic tractography atlas of language connectivity in the developing brain.Brain : a journal of neurology · 2021Article
- Dynamic tractography-based localization of spike sources and animation of spike propagations.Epilepsia · 2021Article
- Spontaneous modulations of high-frequency cortical activity.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Four-dimensional tractography animates propagations of neural activation via distinct interhemispheric pathways.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Intraoperative Brain Mapping by Cortico-Cortical Evoked Potential.Frontiers in human neuroscience · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo determine the optimal depth electrode montages for the assessment of effective connectivity based on single-pulse electrical stimulation (SPES). To determine the effect of SPES locations on the extent of resulting neuronal propagations.
methodsWe studied 14 epilepsy patients who underwent invasive monitoring with depth electrodes and measurement of cortico-cortical evoked potentials (CCEPs) and cortico-cortical spectral responses (CCSRs). We determined the effects of electrode montage and stimulus sites on the CCEP/CCSR amplitudes.
resultsBipolar and Laplacian montages effectively reduced the degree of SPES-related signal deflections at extra-cortical levels, including outside the brain, while maintaining those at the cortical level. SPES of structures more proximal to the deep white matter, compared to the cortical surface, elicited greater CCEPs and CCSRs.
conclusionsOn depth electrode recording, bipolar and Laplacian montages are suitable for measurement of near-field CCEPs and CCSRs. SPES of the white matter axons may induce neuronal propagations to extensive regions of the cerebral cortex. SIGNIFICANCE: This study helps to establish the practical guidelines on the diagnostic use of CCEPs/CCSRs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.