Evidence map›Paper›PMID 33129872›Full record

ArticleUrology2021

Utilizing 3D Printing and Hydrogel Casting for the Development of Patient-Specific Rehearsal Platforms for Robotic Assisted Partial Nephrectomies.

Ahmed Ghazi, Patrick Saba, Rachel Melnyk, Jean Joseph

Abstract readVideo-Audio Media
In one paragraph

Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ahmed GhaziUniversity of Rochester Medical Center, Division Department of Urology, 601 Elmwood Ave, Rochester, NY. Electronic address: Ahmed_Ghazi@URMC.rochester.edu.
Patrick SabaUniversity of Rochester Medical Center, Division Department of Urology, 601 Elmwood Ave, Rochester, NY.
Rachel MelnykUniversity of Rochester Medical Center, Division Department of Urology, 601 Elmwood Ave, Rochester, NY.
Jean JosephUniversity of Rochester Medical Center, Division Department of Urology, 601 Elmwood Ave, Rochester, NY.

Funding

Development and validation of high fidelity, patient specific, kidney phantoms for surgical rehearsalsR03EB027300 · NIBIB · UNIVERSITY OF ROCHESTER · PI GHAZI, AHMED · 2020 to 2021
$154k
NIBIB NIH HHS R03 EB027300
6 · The paper itself

Abstract

backgroundThree-dimensional (3D) printing technology has been utilized to create patient-specific (PS) replicas as visual aids for surgical planning.

objectivesDevelop anatomically accurate, realistic, PS partial nephrectomy platforms suitable for pre-operative surgical rehearsals using 3D-printing and hydrogel casting. MATERIAL: Patient CT scans were segmented into a computer-aided design (CAD) file and used to create injection casts. Kidney and tumor casts along with hollow vascular and urinary structures were 3D-printed. The hilar structures and tumor were registered into the kidney cast, injected with poly-vinyl alcohol (PVA) hydrogel, and processed to create the kidney phantom. Mechanical and functional testing protocols were completed to confirm that the properties of PVA matched the live tissue.

resultsThe 7%-3freeze/thaw PVA best recreated the mechanical and functional properties of porcine kidneys, while anatomical verification showed ≤1 mm deviation of the kidney and tumor from the patient anatomy and ≤3 mm for the hilar structures. PS rehearsal platforms were fabricated using these methods for 8 patients (average tumor size 5.92 cm and nephrometry score 9.8). A positive correlation was found for warm ischemia time and estimated blood loss between rehearsals and live surgeries.

conclusionThis reproducible method shows high anatomical accuracy, realistic tissue properties, and translational effects between rehearsals and live surgery. To determine the effects on patient outcomes, future studies will compare the impact of completing a pre-operative rehearsal vs standard surgical preparation.

Indexed as

Models, AnatomicPrinting, Three-DimensionalComputer-Aided DesignHumansHydrogelsNephrectomyPolyvinylsPreoperative PeriodRobotic Surgical ProceduresHydrogelsPolyvinyls

Identifiers

PMID33129872
PMCPMC7785697

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.