Evidence map›Paper›PMID 33129813›Full record

ArticleAmerican journal of ophthalmology2021

Association of Visual Acuity with Eye-Related Quality of Life and Functional Vision Across Childhood Eye Conditions.

David A Leske, Sarah R Hatt, Suzanne M Wernimont, Yolanda S Castañeda, Christina S Cheng-Patel, Laura Liebermann, Eileen E Birch, Jonathan M Holmes

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Association of primary congenital glaucoma with quality of life in children and their families.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  10. Amblyopia and the whole child.Progress in retinal and eye research · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David A LeskeDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Sarah R HattDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Suzanne M WernimontDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Yolanda S CastañedaRetina Foundation of the Southwest, Dallas, Texas, USA.
Christina S Cheng-PatelRetina Foundation of the Southwest, Dallas, Texas, USA.
Laura LiebermannDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Eileen E BirchRetina Foundation of the Southwest, Dallas, Texas, USA; University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jonathan M HolmesDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA; Department of Ophthalmology and Vision Science, University of Arizona-Tucson, Tucson, Arizona. Electronic address: jmholmes@arizona.edu.
Mayo Clinic · USRetina Foundation of the Southwest · USUniversity of Arizona · US

Funding

Pediatric Eye Disease Investigator Group Coordinating CenterU10EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI KRAKER, RAYMOND · 1997 to 2018
$75.2M
Pediatric Eye Disease Investigator Group NetworkUG1EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI Raymond Kraker, Stacy Pineles · 2019 to 2026
$53.7M
Binocular Vision, Amblyopia, and Refractive Development in EsotropiaR01EY022313 · NEI · RETINA FOUNDATION OF THE SOUTHWEST · PI Eileen Elizabeth Birch · 2012 to 2026
$7.0M
Outcome Measures for Clinical Trials in Pediatric Eye Care and StrabismusR01EY024333 · NEI · MAYO CLINIC ROCHESTER · PI FAUTSCH, MICHAEL P. · 2014 to 2018
$3.3M
NEI NIH HHS R01 EY022313NEI NIH HHS R01 EY024333NEI NIH HHS U10 EY011751NEI NIH HHS UG1 EY011751
6 · The paper itself

Abstract

purposeWe evaluated relationships between visual acuity (VA) and eye-related quality of life and functional vision in children, across a spectrum of pediatric eye conditions, using the Pediatric Eye Questionnaire (PedEyeQ).

designCross-sectional study.

methodsThree hundred ninety-seven children (5-11 years of age) with an eye condition and 104 visually normal control subjects completed the Child PedEyeQ (functional vision, bothered by eyes/vision, social, and frustration/worry domains). One parent for each child completed the Proxy PedEyeQ (same domains as child plus eye care) and parent PedEyeQ (impact on parent and family, worry about child's eye condition, worry about child's self-perception and interactions, and worry about functional vision domains). Each domain was Rasch-scored and Spearman rank correlations were calculated to evaluate relationships between better-seeing-eye and worse-seeing-eye VA and PedEyeQ domain score.

resultsThere was a significant relationship between poorer better-seeing-eye VA and lower (worse) PedEyeQ score on 2 of 4 child domains (e.g., functional vision, r = -0.1474; P = .005), on 2 of 5 proxy PedEyeQ domains (e.g., functional vision, r = -0.2183; P < .001), and on 2 of 4 parent PedEyeQ domains (e.g., impact on parent and family, r = -0.1607; P = .001). Worse-seeing-eye VA was associated with lower PedEyeQ scores across all child, proxy and parent domains (P < .01 for each) with the exception of the child social domain (P = .15).

conclusionsBoth better-seeing-eye and worse-seeing-eye VA were associated with functional vision and eye-related quality of life in children, assessed using the PedEyeQ, although other factors may also influence relationships. These data further validate using the PedEyeQ across pediatric eye conditions.

Indexed as

Quality of LifeVisual AcuityChildChild, PreschoolCross-Sectional StudiesFemaleFollow-Up StudiesHumansMalePrognosisProspective StudiesSurveys and QuestionnairesVision Disorders

Identifiers

PMID33129813
PMCPMC7979455
OpenAlexW3097963258

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.