Observational studyClinical nutrition (Edinburgh, Scotland)2021
Association of bioelectric impedance analysis body composition and disease severity in COVID-19 hospital ward and ICU patients: The BIAC-19 study.
Observational study in Clinical nutrition (Edinburgh, Scotland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Phase angle and COVID-19: A systematic review with meta-analysis.Reviews in endocrine & metabolic disorders · 2023Pooled it
- Prevalence and clinical implications of abnormal body composition phenotypes in patients with COVID-19: a systematic review.The American journal of clinical nutrition · 2023Pooled it
- Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Association between phase angle and adverse clinical outcomes in hospitalized patients with COVID-19: A systematic review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022Pooled it
- Metrology in Bioelectrical Impedance Analysis (BIA): From Measurement Science to Clinical and Research Applications.Sensors (Basel, Switzerland) · 2026Review
- Body composition-guided protein dosing in critically ill patients: a before-and-after study (PROGRESS-ICU).Critical care (London, England) · 2026Observational
- Modernization of Nutritional Assessment in Population Surveys: Integrating Anthropometry, Body Composition, and Biomarkers in the Digital Era.Current nutrition reports · 2026Review
- Phase Angle in Bioelectrical Impedance: New Perspectives in Health and Body Composition Assessment.Physiological research · 2025Observational
- Assessing the influence of TP53 polymorphisms and haplotypes on bioelectrical impedance analysis parameters and nutritional status in aging Iranian population.Molecular biology reports · 2025Article
- Risk of poor nutritional status and nutrition-related complaints in individuals attending a primary care dietitian after a COVID-19 infection: A prospective cohort study.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2025Observational
- Advancing Nutritional Care Through Bioelectrical Impedance Analysis in Critical Patients.Nutrients · 2025Review
- Handgrip strength as a prognostic factor for COVID-19 mortality among older adult patients admitted to the intensive care unit (ICU): a comparison Alpha (B.1.1.7) and Delta (B.1.617.2) variants.Scientific reports · 2024Article
- The Effect of Passive Dehydration on Phase Angle and Body Composition: A Bioelectrical Impedance Analysis.Nutrients · 2024Article
- Mendelian randomization analysis reveals higher whole body water mass may increase risk of bacterial infections.BMC medical genomics · 2024Article
- Total and segmental phase angle in a cohort of hospitalised patients with COVID-19: mortality prediction and changes throughout hospitalisation.The British journal of nutrition · 2024Article
- Gender-Related Effectiveness of Personalized Post-COVID-19 Rehabilitation.Journal of clinical medicine · 2024Article
- Cardiovascular autonomic evaluation and body fat analysis in COVID-19-recovered patients in Dakshina Kannada, India.Journal of education and health promotion · 2024Article
- Reliability, biological variability, and accuracy of multi-frequency bioelectrical impedance analysis for measuring body composition components.Frontiers in nutrition · 2024Article
- Comparison of Bioelectrical Impedance Analysis (BIA)-Derived Parameters in Healthy Volunteers and Critically Ill Patients.Life (Basel, Switzerland) · 2023Article
- Visceral fat area measured by electrical bioimpedance as an aggravating factor of COVID-19: a study on body composition.BMC infectious diseases · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current severe acute respiratory syndrome coronavirus 2 pandemic is unprecedented in its impact. It is essential to shed light on patient characteristics that predispose to a more severe disease course. Obesity, defined as a BMI>30 kg/m
methodsWe performed an observational cross-sectional cohort study. Bioelectric impedance analysis was conducted amongst all confirmed COVID-19 patients admitted to the ward or ICU of our hospital in the Netherlands, between April 10 and 17, 2020. Body water measurements and derived values were recalculated to dry weight, using a standard ratio of extracellular water to total body water of 0.38. Data were compared between the ward and ICU patients, and regression models were used to assess the associations between baseline characteristics, body composition, and several indicators of disease severity, including a composite score composed of mortality, morbidity, and ICU admission.
resultsFifty-four patients were included, of which 30 in the ward and 24 in the ICU. The mean age was 67 years (95%-CI 64-71), and 34 (63%) were male. Mean BMI was 29.7 (95%-CI 28.2-31.1) kg/m
conclusionWe found no significant associations between body composition, including fat mass, visceral fat area, and fat-free mass, and disease severity in our population of generally overweight COVID-19 patients. A lower phase angle did increase the odds of severe COVID-19. We believe that factors other than body composition play a more critical role in the development of severe COVID-19.
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