Evidence map›Paper›PMID 33129278›Full record

ArticleBMC medical research methodology2020

Pharmacist and patient perspectives on recruitment strategies for randomized controlled trials: a qualitative analysis.

Jane M Fletcher, Terry Saunders-Smith, Braden J Manns, Ross Tsuyuki, Brenda R Hemmelgarn, Marcello Tonelli, David J T Campbell

Registry-linked trialAbstract read
In one paragraph

Article in BMC medical research methodology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02579655 (Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02579655 nacompletednot on this map

Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study

TypeinterventionalSponsorUniversity of CalgaryRan2015 to 2021Enrolled4,764ConditionsCoronary Disease, Stroke, Chronic Kidney Disease, Heart FailureArmsCopayment Elimination, Personalized Education
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jane M FletcherDepartment of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Terry Saunders-SmithDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Braden J MannsDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Ross TsuyukiDepartment of Pharmacology, Faculty of Medicine and Dentistry, 2J2.00 WC Mackenzie Health Sciences Centre, University of Alberta, 8440 112 St. NW, Edmonton, AB, T6G 2R7, Canada.
Brenda R HemmelgarnDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Marcello TonelliDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 1N4, Canada.
David J T CampbellDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 1N4, Canada. dcampbel@ucalgary.ca.ORCID 0000-0002-5570-3630

Funding

Alberta Innovates - Health Solutions 201300672Canadian Institute of Health Research - Foundation Grant 148441University of Calgary Clinical Research Fund CRF15-018
6 · The paper itself

Abstract

backgroundAlthough recruitment is a major challenge for most randomized controlled trials, few report on the difficulties of recruitment, or how it might be enhanced. The objective of our study was to qualitatively explore the experiences of both patients and pharmacists related to recruitment for ACCESS, a large trial involving low-income seniors, given that two of our most successful recruitment strategies were direct patient recruitment materials and use of community pharmacists.

methodsUsing qualitative descriptive methods, we collected data from pharmacists and study participants. Pharmacists were asked about their impressions of the study, as well as challenges they faced and methods they used to recruit potential participants. Focus groups with trial participants centered on the patient recruitment materials. Interviews and focus groups were recorded, transcribed and analyzed using thematic analysis.

resultsPharmacists noted that their first impressions of the study were positive as they described being enticed to help the study team by the potential benefit of copayment elimination for their patients and the low time commitment. Pharmacists noted they were more likely to recruit if they were well informed on the study, as they could answer their patients' questions. Participants noted that their primary motivations for participating were the tangible benefits of free medications and the intrinsic value of participating in research.

conclusionsWe noted that recruitment through pharmacies was an effective method as most patients have trusting relationships with their pharmacist. To optimize recruitment through pharmacies, study procedures should be straightforward, and pharmacists need to be equipped with good knowledge of the study. When promoting a study to potential participants, messaging should ensure the individuals are aware of the tangible benefits of participation while still presenting a full overview of the trial.

trial registrationTrial Registration Number: NCT02579655 - initially registered Oct 19, 2015.

Indexed as

PharmacistsResearch DesignFocus GroupsHumansPatient SelectionQualitative ResearchRandomized Controlled Trials as TopicChronic diseaseEducationMedicationParticipant focus groupPharmacistQualitativeRandomized controlled trialsRecruitmentSenior

Identifiers

PMID33129278
PMCPMC7603682

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.