Evidence map›Paper›PMID 33128946›Full record

ArticleSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2021

A modular template for the design of thiol-triggered sensors and prodrugs.

Jessica Renee Knight, Yingying Wang, Shi Xu, Wei Chen, Clifford E Berkman, Ming Xian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica Renee KnightDepartment of Chemistry, Washington State University, Pullman, WA 99164, USA.
Yingying WangDepartment of Chemistry, Washington State University, Pullman, WA 99164, USA.
Shi XuDepartment of Chemistry, Brown University, Providence, RI 02912, USA.
Wei ChenDepartment of Chemistry, Washington State University, Pullman, WA 99164, USA.
Clifford E BerkmanDepartment of Chemistry, Washington State University, Pullman, WA 99164, USA.
Ming XianDepartment of Chemistry, Brown University, Providence, RI 02912, USA. Electronic address: ming_xian@brown.edu.

Funding

Chemical Tools for Understanding the Redox Biology of Reactive Sulfur SpeciesR01GM125968 · NIGMS · WASHINGTON STATE UNIVERSITY · PI XIAN, MING · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM125968
6 · The paper itself

Abstract

A unique reaction between thiols (RSH) and alkyl sulfonylbenzothiazole was discovered. This reaction was specific for thiols and produced a sulfinic acid (RSO

Indexed as

ProdrugsSulfhydryl CompoundsCyclizationProdrugsSulfhydryl CompoundsBiothiolsFluorescent probeProdrugSulfinic acid

Identifiers

PMID33128946
PMCPMC7736145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.