Evidence map›Paper›PMID 33128852›Full record

ArticleJournal of veterinary internal medicine2020

Seizures in dogs under primary veterinary care in the United Kingdom: Etiology, diagnostic testing, and clinical management.

Alexander Erlen, Heidrun Potschka, Holger A Volk, Carola Sauter-Louis, Dan G O'Neill

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Alexander ErlenInstitute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians-University, Munich, Germany.ORCID https://orcid.org/0000-0002-2193-4684
Heidrun PotschkaInstitute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians-University, Munich, Germany.
Holger A VolkDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hannover, Germany.
Carola Sauter-LouisInstitute of Epidemiology, Friedrich-Loeffler-Institut, Greifswald, Germany.
Dan G O'NeillPathobiology and Population Health, The Royal Veterinary College, Hatfield, United Kingdom.ORCID https://orcid.org/0000-0003-1115-2723
Ludwig-Maximilians-Universität München · DEFriedrich-Loeffler-Institut · DERoyal Veterinary College · GBUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

Bayer Animal Health GmbH
6 · The paper itself

Abstract

backgroundAlthough seizures are common in dogs, limited published information is available on the classifications of seizures, diagnostic approaches, or clinical management of seizure-affected patients in the veterinary primary care setting.

objectivesExplore seizure etiology, diagnostic testing, and clinical management of seizure-affected dogs in the primary care veterinary setting. ANIMALS: A total of 455 553 dogs in VetCompass.

methodsCross-sectional analysis by cohort clinical data.

resultsFrom 2834 incident seizure cases, we identified 579 (20.5%) dogs with epilepsy based on the International Veterinary Epilepsy Task Force (IVETF) classification system, including 484 (17.1%) with idiopathic epilepsy, 95 (3.4%) with structural epilepsy, and 179 dogs (6.3%) with reactive seizures. In their clinical first opinion records, 245 (8.6%) cases were recorded with epilepsy. Overall, 1415 (49.9%) cases received diagnostic evaluation equivalent to or higher than IVETF Tier 1 diagnostic testing. Being <12 years of age and being insured were risk factors for receiving IVETF Tier 1 or higher diagnostic evaluation among seizure cases. Anti-seizure drug (ASD) treatment was not prescribed for 1960/2834 (69.2%) dogs in association with the incident seizure event. Of the remainder, 719 (25.3%) dogs received 1 ASD, whereas 155 (5.5%) an ASD combination. CONCLUSION AND CLINICAL IMPORTANCE: The differences between seizure classifications in the clinical records and those retrospectively assigned by the researchers support the need for clearer diagnostic guidelines in clinical practice. Insured dogs and dogs <12 years of age were more likely to receive advanced diagnostic evaluation, suggesting that financial and perceived prognostic factors influence case management.

Indexed as

Dog DiseasesSeizuresAnimalsAnticonvulsantsCross-Sectional StudiesDiagnostic Techniques and ProceduresDogsPrimary Health CareRetrospective StudiesUnited KingdomAnticonvulsantscanineepilepsyfirst-opinionfitIVETFrisk factorVetCompass

Identifiers

PMID33128852
PMCPMC7694840
OpenAlexW3095023457

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.