Evidence map›Paper›PMID 33128777›Full record

ArticleInternational journal of cancer2021

Short tandem repeat profiling for the authentication of cancer stem-like cells.

Paola Visconti, Federica Parodi, Barbara Parodi, Lucia Casarino, Paolo Romano, Mariachiara Buccarelli, Roberto Pallini, Quintino Giorgio D'Alessandris, Andrea Montori, Emanuela Pilozzi and 1 more

Abstract read
In one paragraph

Article in International journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  12. Highly Potent and Selective Dopamine DJournal of medicinal chemistry · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paola ViscontiIRCCS Ospedale Policlinico San Martino, Interlab Cell Line Collection (ICLC), Biological Resource Center (CRB-HSM), Genoa, Italy.
Federica ParodiIRCCS Ospedale Policlinico San Martino, Interlab Cell Line Collection (ICLC), Biological Resource Center (CRB-HSM), Genoa, Italy.ORCID 0000-0002-3048-2691
Barbara ParodiIRCCS Ospedale Policlinico San Martino, Interlab Cell Line Collection (ICLC), Biological Resource Center (CRB-HSM), Genoa, Italy.
Lucia CasarinoDepartment of Legal and Forensic Medicine, University of Genoa, Genoa, Italy.
Paolo RomanoIRCCS Ospedale Policlinico San Martino, Proteomics Service, Scientific Direction, Genoa, Italy.
Mariachiara BuccarelliDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
Roberto PalliniFondazione Policlinico Universitario A. Gemelli IRCCS - Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.ORCID 0000-0002-4611-8827
Quintino Giorgio D'AlessandrisFondazione Policlinico Universitario A. Gemelli IRCCS - Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.
Andrea MontoriDepartment of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", Rome, Italy.
Emanuela PilozziDepartment of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", Rome, Italy.
Lucia Ricci-VitianiDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal and glioblastoma cancer stem-like cells (CSCs) are essential for translational research. Cell line authentication by short tandem repeat (STR) profiling ensures reproducibility of results in oncology research. This technique enables to identify mislabeling or cross-contamination of cell lines. In our study, we provide a reference dataset for a panel of colorectal and glioblastoma CSCs that allows authentication. Each cell line was entered into the cell Line Integrated Molecular Authentication database 2.1 to be compared to the STR profiles of 4485 tumor cell lines. This article also provides clinical data of patients from whom CSCs arose and data on the parent tumor stage and mutations. STR profiles and information of our CSCs are also available in the Cellosaurus database (ExPASy) as identified by unique research resource identifier codes.

Indexed as

Cell Line, TumorMicrosatellite RepeatsNeoplastic Stem CellsAdultAgedAged, 80 and overCell Line AuthenticationColorectal NeoplasmsDatasets as TopicFemaleGene Expression ProfilingGlioblastomaHumansMaleMiddle Agedcell line authenticationcolorectal tumorglioblastomahuman stem-like cell linesshort tandem repeat profiling

Identifiers

PMID33128777
PMCPMC7894552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.