Evidence map›Paper›PMID 33128773›Full record

ReviewClinical and experimental immunology2021

Th22 response induced by Mycobacterium tuberculosis strains is closely related to severity of pulmonary lesions and bacillary load in patients with multi-drug-resistant tuberculosis.

B R Imperiale, A García, A Minotti, P González Montaner, L Moracho, N S Morcillo, D J Palmero, M Del Carmen Sasiain, S de la Barrera

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Th9 cells provide protective TB immunity.Frontiers in immunology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. International journal of molecular sciences · 2022
    Article
  14. Characterization ofJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

B R ImperialeInstitute of Experimental Medicine (IMEX)-CONICET, National Academy of Medicine, Buenos Aires City, Argentina.ORCID 0000-0003-0198-8746
A GarcíaDr. F.J. Muñiz Hospital, Buenos Aires City, Argentina.
A MinottiInstitute of Experimental Medicine (IMEX)-CONICET, National Academy of Medicine, Buenos Aires City, Argentina.
P González MontanerDr. F.J. Muñiz Hospital, Buenos Aires City, Argentina.
L MorachoDr. F.J. Muñiz Hospital, Buenos Aires City, Argentina.
N S MorcilloTuberculosis and Mycobacterioses Laboratory, Dr. Antonio A. Cetrángolo Hospital, Buenos Aires Province, Argentina.
D J PalmeroDr. F.J. Muñiz Hospital, Buenos Aires City, Argentina.
M Del Carmen SasiainInstitute of Experimental Medicine (IMEX)-CONICET, National Academy of Medicine, Buenos Aires City, Argentina.
S de la BarreraInstitute of Experimental Medicine (IMEX)-CONICET, National Academy of Medicine, Buenos Aires City, Argentina.
Academia Nacional de Medicina · ARHospital Muñiz · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of interleukin-22 (IL-22) in the pathogenesis or tissue repair in human tuberculosis (TB) remains to be established. Here, we aimed to explore the ex-vivo and in-vitro T helper 22 (Th22) response in TB patients and healthy donors (HD) induced by different local multi-drug-resistant (MDR) Mvcobacterium tuberculosis (Mtb) strains. For this purpose, peripheral blood mononuclear cells from drug-susceptible (S-TB) MDR-TB patients and HD were stimulated with local MDR strains and the laboratory strain H37Rv. IL-22 and IL-17 expression and senescent status were assessed in CD4

Indexed as

AdultAntigens, BacterialCD4-Positive T-LymphocytesCD57 AntigensCD8-Positive T-LymphocytesFemaleHumansInterferon-gammaInterleukin-17Interleukin-22InterleukinsLeukocytes, MononuclearLungMaleMiddle AgedMycobacterium tuberculosisAntigens, BacterialCD57 AntigensInterferon-gammaInterleukin-17Interleukin-22InterleukinsProgrammed Cell Death 1 ReceptorIL-22multi-drug-resistant tuberculosisMycobacterium tuberculosis strainsTh22 response

Identifiers

PMID33128773
PMCPMC7806416
OpenAlexW3096358249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.