Observational studyJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2020
T-wave inversion as a manifestation of COVID-19 infection: a case series.
Observational study in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Beyond Ischemia: A Curious Case of Electrocardiographic Abnormalities in COVID-19 Without Myocardial Injury.Cureus · 2025Article
- Review
- Clinical Management of New-Onset Atrial Fibrillation in COVID-19 Patients Referred to a Tertiary Cardiac Arrhythmia Center after Hospital Discharge.Journal of clinical medicine · 2022Article
- Myocardial Ischemia in Patients with COVID-19 Infection: Between Pathophysiological Mechanisms and Electrocardiographic Findings.Life (Basel, Switzerland) · 2022Review
- Medium-Term Outcomes in COVID-19.Journal of clinical medicine · 2022Article
- Prevalence, Outcomes, and Management of Ventricular Arrhythmias in COVID-19 Patients.Cardiac electrophysiology clinics · 2022Review
- COVID-19, Acute Myocardial Injury, and Infarction.Cardiac electrophysiology clinics · 2022Review
- Prevalence and Clinical Implications of COVID-19 Myocarditis.Cardiac electrophysiology clinics · 2022Review
- Electrocardiographic Features of Patients with COVID-19: An Updated Review.Cardiac electrophysiology clinics · 2022Review
- Arrhythmogenic Risk and Mechanisms of QT-Prolonging Drugs to Treat COVID-19.Cardiac electrophysiology clinics · 2022Review
- Unusual T-wave changes and extreme QTc prolongation in a 71-year-old man with asymptomatic COVID infection.HeartRhythm case reports · 2022Article
- Increased number of electrocardiogram findings requiring additional cardiac examination in young athletes during the coronavirus disease 2019 pandemic: a case series.The Journal of international medical research · 2021Observational
- Cardiac arrhythmias associated with COVID-19 infection: state of the art review.Expert review of cardiovascular therapy · 2021Review
- Prolonged QT predicts prognosis in COVID-19.Pacing and clinical electrophysiology : PACE · 2021Article
- Electrocardiographic Risk Stratification in COVID-19 Patients.Frontiers in cardiovascular medicine · 2021Article
- Troponin at presentation: A key predictor of chronic myocardial impairment post-myocarditis-A prospective cohort study.JRSM cardiovascular diseaseArticle
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23 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeCardiac involvement with COVID-19 infection has become evident by elevated troponin, cardiac arrhythmias, ST segment elevation, myocarditis, fulminant heart failure, and sudden cardiac death. We aimed to describe the association of COVID-19 and T-wave inversion (TWI) in a large case series.
methodsWe conducted an observational, retrospective study of confirmed COVID-19 cases with at least one electrocardiogram (ECG) in a large hospital in New York City (March 23, 2020-April 23, 2020). Patients with new TWI or pseudonormalization were further analyzed. Mortality and the need for invasive mechanical ventilation were the main outcomes.
resultsA total of 3225 patients were screened; 195 (6%) were selected for further analysis: 181 with TWI and 14 with T-wave pseudonormalization. Mean age was 66 ± 7 years; 51% were male. TWI were more commonly noted in the lateral (71%), followed by anterior (64%), inferior (57%), and septal (26%) leads. A total of 44 patients (23%) had elevated troponin. A total of 50 patients died (26%). Mortality rates of 35%, and 52% were observed in patients with diffuse TWI, and elevated troponin, respectively. Mortality rate of 80% was observed in patients with both elevated troponin and diffuse TWI. Additionally, 30% of the entire cohort and 58% of patients with elevated troponin required invasive mechanical ventilation.
conclusionOur study demonstrates that new TWI is a relatively common finding in COVID-19 patients. Importantly, our findings suggest that new TWI or T-wave pseudonormalization, particularly with elevated troponin, was associated with higher rates of mechanical ventilation and in-hospital mortality.
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