Evidence map›Paper›PMID 33128648›Full record

SynthesisSurgical and radiologic anatomy : SRA2021

A systematic review of the surgical anatomy of the orbital apex.

Ӧ Engin, G F J P M Adriaensen, F W A Hoefnagels, P Saeed

Abstract readSystematic Review
In one paragraph

Synthesis in Surgical and radiologic anatomy : SRA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Reversible Orbital Apex Syndrome.Journal of eye movement research · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Optic foramen location on computed tomography.Archives of craniofacial surgery · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ӧ EnginOrbital Center, Ophthalmology Department, Amsterdam UMC, location AMC, Amsterdam, The Netherlands. o.engin@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-4961-5033
G F J P M AdriaensenOrbital Center, Ophthalmology Department, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
F W A HoefnagelsOrbital Center, Ophthalmology Department, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
P SaeedOrbital Center, Ophthalmology Department, Amsterdam UMC, location AMC, Amsterdam, The Netherlands. p.saeed@amsterdamumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe orbital apex is the narrowest part of the orbit, housing the link between the intracranial cavity and orbit. Knowledge of orbital apex anatomy is crucial to selecting a surgical approach and reducing the risk of complications. Our purpose is to summarize current knowledge on surgical anatomy and attempt to reach a consensus on definition of the orbital apex.

methodsThe online databases of Embase, the Cochrane library, Web of Science and PubMed (MEDLINE) were queried in a comprehensive bibliographic search on the (surgical) anatomy of the orbital apex and consisted of a combination of two subjects, using indexed terms and free text: "Orbital Apex" and "Orbital Anatomy."

resultsA total of 114 relevant papers were included in this review. Numerous anatomical variations are described in the literature. Variations of the optic canal include duplication (0.64%) and keyhole anomaly (2.65%). Variations in pneumatization of the anterior clinoid process were unilateral in almost 10%, bilateral in 9%, and normal in 72%. A rare variant of the superior orbital fissure (SOF) is Warwick's foramen, which appears as if the lowest portion of the SOF was separated from the main fissure by a transverse bony bridge.

conclusionThe definition of the orbital apex varies in the literature, and further research would most likely identify additional variations. A universal definition reporting these variations and pathology and imaging findings is essential for determining the optimal surgical approach to the orbital apex.

Indexed as

Anatomic VariationHumansIntraoperative ComplicationsOrbitAnatomyApexOrbitSurgery

Identifiers

PMID33128648
PMCPMC7843489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.