Evidence map›Paper›PMID 33128571›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Physiologic colonic uptake of

Lena Cvetkovic, Claudine Régis, Corentin Richard, Lisa Derosa, Antoine Leblond, Julie Malo, Meriem Messaoudene, Antoine Desilets, Wiam Belkaid, Arielle Elkrief and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  5. Multi-Organ metabolic profiling with [European journal of nuclear medicine and molecular imaging · 2025
    Article
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  7. Article
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  9. Can physiologic colonic [European journal of nuclear medicine and molecular imaging · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Lena Cvetkovic *Department of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Claudine Régis *Department of Radiology and Nuclear Medicine, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Corentin RichardCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, Québec, Canada.
Lisa DerosaDepartment of Tumor Immunology and Immunotherapy INSERM U1015, Gustave Roussy Cancer Center, Villejuif, France.
Antoine LeblondDepartment of Radiology and Nuclear Medicine, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Julie MaloDepartment of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Meriem MessaoudeneDepartment of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Antoine DesiletsDepartment of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Wiam BelkaidDepartment of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Arielle ElkriefDepartment of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Bertrand RoutyDepartment of Hematology and Oncology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada. bertrand.routy@umontreal.ca.
Daniel JuneauCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, Québec, Canada. daniel.juneau@umontreal.ca.
Centre Hospitalier de l’Université de Montréal · CACentre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec · CAInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune checkpoint inhibitors (ICI) represent the backbone treatment for advanced non-small cell lung cancer (NSCLC). Emerging data suggest that increased gut microbiome diversity is associated with favorable response to ICI and that antibiotic-induced dysbiosis is associated with deleterious outcomes.

methodsSeventy-one patients with advanced NSCLC who underwent a PET/CT prior to ICI were identified. Blinded colonic contouring was performed for each colon segment and patients were stratified according to the median of the average colon SUV

resultsThe high colon SUV

conclusionsLower colon physiologic

Indexed as

Carcinoma, Non-Small-Cell LungGastrointestinal MicrobiomeLung NeoplasmsColonFluorodeoxyglucose F18HumansImmune Checkpoint InhibitorsPositron Emission Tomography Computed TomographyPrognosisFluorodeoxyglucose F18Immune Checkpoint Inhibitors18F-FDG colonic uptakeGut microbiomeImmunotherapyMetagenomicsNon-small cell lung cancer

Identifiers

PMID33128571
OpenAlexW3096950825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.