ArticleJournal of clinical laboratory analysis2021
Mean platelet volume/platelet count ratio predicts severe pneumonia of COVID-19.
Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Are platelet volume indices of clinical use in COVID-19? A systematic review.Frontiers in cardiovascular medicine · 2022Pooled it
- Article
- Comparative Study on the Effect of Vitamin D Deficiency on Platelet Indices in COVID-19 and Hepatitis C Patients; an Observational Comparative Study.Health science reports · 2026Article
- Red Cell Distribution Width (RDW), Platelets and Platelet Index MPV/PLT Ratio as Specific Time Point Predictive Variables of Survival Outcomes in COVID-19 Hospitalized Patients.Journal of clinical medicine · 2025Article
- Effective new predictors of prognosis and comparison of multidisciplinary treatment options in acute mesenteric ischemia.Northern clinics of Istanbul · 2025Article
- Outcomes of Cancer Patients Affected by COVID-19 in Different Settings: A Retrospective Study in Lebanon.Cancer reports (Hoboken, N.J.) · 2024Article
- Predictive ability of complete blood count, mean platelet ratio, mean platelet volume, and neutrophil/lymphocyte ratio for severe pneumonia among RT-PCR or radiologically proven COVID-19 patients.Journal of family medicine and primary care · 2024Article
- Evaluation of three common scoring systems in COVID-19 patients: neutrophil-lymphocyte ratio (NLR), The Acute Physiology and Chronic Health Evaluation II (APACHE II), and C-reactive protein (CRP).Annals of medicine and surgery (2012) · 2024Article
- The effect of vitamin D deficiency on platelet parameters in patients with COVID-19.Frontiers in cellular and infection microbiology · 2024Article
- The association between mean platelet volume and poor outcome in patients with COVID-19: Systematic review, meta-analysis, and meta-regression.Journal of the Intensive Care Society · 2023Article
- Angiotensin converting enzyme 2 gene expression and markers of oxidative stress are correlated with disease severity in patients with COVID-19.Molecular biology reports · 2023Article
- Predictive value of platelet-related parameters combined with pneumonia severity index score for mortality rate of patients with severe pneumonia.African health sciences · 2023Article
- Clinical Value of Inflammatory Biomarkers in Determining Severity of COVID-19.Journal of acute medicine · 2023Article
- DIET: Conditional independence testing with marginal dependence measures of residual information.Proceedings of machine learning research · 2023Article
- Biological Markers to Predict Outcome in Mechanically Ventilated Patients with Severe COVID-19 Living at High Altitude.Journal of clinical medicine · 2023Article
- Comparative Analysis of Red Blood Cells, White Blood Cells, Platelet Count, and Indices in Type 2 Diabetes Mellitus Patients and Normal Controls: Association and Clinical Implications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Could platelet indices have diagnostic properties in children with COVID-19?Journal of clinical laboratory analysis · 2022Article
- On-Admission Anemia and Survival Rate in COVID-19 PatientsIranian biomedical journal · 2022Article
- Decoding clinical biomarker space of COVID-19: Exploring matrix factorization-based feature selection methods.Computers in biology and medicine · 2022Article
- Clinical and Laboratory Approach to Diagnose COVID-19 Using Machine Learning.Interdisciplinary sciences, computational life sciences · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAlthough platelet mean volume/platelet count ratio (MPR) is considered to be a crucial marker of inflammatory and infectious diseases, the relationship between MPR and novel coronavirus infectious disease 2019 (COVID-19) remains unclear.
methodsIn this retrospective study, 85 patients with confirmed COVID-19 were enrolled and divided into low and high MPR group. Data from repeated measures were compared by the generalized estimating equations. Cox regression analyses were performed to assess the impact of MPR on the incidence of severe pneumonia (SP), with inverse probability of treatment weighting (IPTW) used to reduce confounding bias. The primary outcome is the incidence of SP of COVID-19.
resultsDuring follow-up, 17 (20.0%) patients were developed to SP. Compared with mild patients, patients with SP developed showed a higher MPR level at baseline, day 1, day 2, and day 3 after admission (P = .005, P = .015, P = .009, and P = .032, respectively). Kaplan-Meier method showed a higher incidence of SP in the high MPR group than the low MPR group (log-rank test = 10.66, P = .001). After adjustment, high MPR was associated with an elevated incidence of SP (HR, 5.841, 95% CI, 1.566-21.791, P = .009). The IPTW method also suggested that MPR was a significant factor related to the incidence of SP (HR, 8.337, 95% CI, 4.045-17.182, P < .001).
conclusionHigh MPR level is an independent risk factor for severe pneumonia in patients with COVID-19.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.