Evidence map›Paper›PMID 33128335›Full record

Observational studyClinical obesity2021

Prenatal exposure to gestational diabetes is associated with anxiety and physical inactivity in children during COVID-19.

Jasmin M Alves, Alexandra G Yunker, Alexis DeFendis, Anny H Xiang, Kathleen A Page

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Clinical obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Gestational Diabetes: An Update 60 Years After O'Sullivan and Mahan.The Journal of clinical endocrinology and metabolism · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jasmin M AlvesDivision of Endocrinology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-0837-9858
Alexandra G YunkerDivision of Endocrinology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-1997-4775
Alexis DeFendisDivision of Endocrinology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Anny H XiangDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.ORCID https://orcid.org/0000-0003-2786-1268
Kathleen A PageDivision of Endocrinology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-9083-6615
University of Southern California · USKaiser Permanente · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Neuroendocrine Systems involved in Early-life Programming for Obesity and DiabetesR01DK116858 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PAGE, KATHLEEN ALANNA, XIANG, ANNY H · 2019 to 2023
$3.5M
The effects of in utero exposure to gestational diabetes on hippocampal structure and functionF31MH115640 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ALVES, JASMIN · 2018 to 2019
$90k
American Diabetes Association Pathway Accelerator Award #1-14-ACE-36National Institute Of Mental Health of the National Institutes of Health F31MH115640National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK116858NCATS NIH HHS UL1 TR001855NIDDK NIH HHS R01 DK116858NIMH NIH HHS F31 MH115640Southern California Clinical and Translational Science Institute (SC CTSI) NIH UL1TR001855
6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) is associated with adverse child mental health outcomes and reduced physical activity. Moreover, prenatal exposure to gestational diabetes (GDM) is associated with increased risk for adverse psychological outcomes in children.

objectivesAssess prenatal exposure to GDM on anxiety levels and physical activity in children during the COVID-19 pandemic.

methodsSixty-five children age 9 to 15 reported their physical activity and anxiety levels using the 24-hours physical activity recall and the State-Trait Anxiety Inventory for Children via phone or video meetings. Prenatal exposure to GDM was obtained from maternal electronic medical records.

resultsThe 38 GDM-exposed children reported significantly higher anxiety levels and were less likely to engage in any vigorous physical activity (VPA) (5% vs 30%) compared to the 27 GDM-unexposed children. Lower levels of physical activity were significantly associated with higher levels of anxiety. Less engagement in VPA explained 75% of the association between GDM exposure and anxiety levels.

conclusionsEngaging in physical activity during the COVID-19 pandemic may be beneficial for reducing anxiety, particularly amongst GDM-exposed children.

Indexed as

AdultAnxiety DisordersBody Mass IndexChildCOVID-19Diabetes, GestationalExerciseFemaleFollow-Up StudiesHumansMalePandemicsPregnancyPrenatal Exposure Delayed EffectsRetrospective StudiesRisk Factorsanxietychildrencoronavirus disease 2019gestational diabetes mellitusphysical activity

Identifiers

PMID33128335
PMCPMC11789531
OpenAlexW3095082494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.