ArticleThe international journal of cardiovascular imaging2021
Influence of chest conformation on myocardial strain parameters in healthy subjects with mitral valve prolapse.
Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Echocardiographic evaluation of left ventricular function in patients with mitral regurgitation: a meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Echocardiographic assessment of left ventricular mechanics in individuals with mitral valve prolapse: a systematic review and meta-analysis.The international journal of cardiovascular imaging · 2024Pooled it
- Beyond Left Ventricular and Left Atrial Strain: The Need for Comprehensive Four-Chamber Mechanical Assessment during the Preclinical Phase of Cardiovascular Disease.Echocardiography (Mount Kisco, N.Y.) · 2026Review
- From Modified Haller Index to a Novel Patented Anatomical Measurement Device: Engineering Development, Validation, and Clinical Applications of Non-Invasive Thoracic Morphometry.Bioengineering (Basel, Switzerland) · 2026Review
- Unmasking Risk in Mitral Regurgitation: Prognostic Value of Exercise Stress Echocardiography-A Systematic Review.Journal of clinical medicine · 2026Review
- Diagnostic Performance of Relative Apical Sparing Across Cardiac Diseases: A Multimodality Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Ethnic Variation in Left Ventricular Size and Mechanics During Healthy Pregnancy: A Systematic Review of Asian and Western Cohorts.Journal of clinical medicine · 2025Review
- Does Preliminary Chest Shape Assessment Improve the Prognostic Risk Stratification of Symptomatic Individuals with Primary Mitral Regurgitation? A Narrative Review of Traditional and Innovative Prognostic Indicators.Journal of clinical medicine · 2025Review
- Mitral Valve Prolapse in Athletes: Prevalence, Arrhythmic Associations, and Clinical Implications-A Systematic Review.Journal of clinical medicine · 2025Review
- Prevalence of Mitral Valve Prolapse Among Individuals with Pectus Excavatum: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2024Review
- Echocardiographic evaluation of left ventricular mechanics in sarcoidosis patients without overt heart disease: a systematic review and meta-analysis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024Article
- Comparison of dimensions and functional features of mitral and tricuspid annuli in the same healthy adults: insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study.Quantitative imaging in medicine and surgery · 2024Article
- Modified Haller index validation and correlation with left ventricular strain in a cohort of subjects with obesity and without overt heart disease.Internal and emergency medicine · 2022Article
- Molecular Approaches and Echocardiographic Deformation Imaging in Detecting Myocardial Fibrosis.International journal of molecular sciences · 2022Review
- Comprehensive assessment of biventricular myocardial function by two-dimensional speckle tracking echocardiography in infants of gestational diabetic mothers.Acta diabetologica · 2022Article
- Liver stiffness measurement identifies subclinical myocardial dysfunction in non-advanced non-alcoholic fatty liver disease patients without overt heart disease.Internal and emergency medicine · 2022Article
- Influence of chest wall conformation on spirometry parameters and outcome in mild-to-moderate idiopathic pulmonary fibrosis.Internal and emergency medicine · 2022Article
- Usefulness of second trimester left ventricular global longitudinal strain for predicting adverse maternal outcome in pregnant women aged 35 years or older.The international journal of cardiovascular imaging · 2022Article
- Does chest shape influence exercise stress echocardiographic results in patients with suspected coronary artery disease?Internal and emergency medicine · 2022Article
- Appropriate use criteria implementation with modified Haller index for predicting stress echocardiographic results and outcome in a population of patients with suspected coronary artery disease.The international journal of cardiovascular imaging · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chest shape might affect myocardial strain parameters. However, the relationship between myocardial strain parameters and chest conformation has not been previously investigated in subjects with mitral valve prolapse (MVP). Between April 2019 and May 2020, 60 healthy subjects (50.1 ± 8.6 year/old, 46.6% females) with MVP and mild-to-moderate mitral regurgitation, and 60 controls matched by age, sex, and cardiovascular risk factors were consecutively studied. Participants underwent modified Haller index (MHI) assessment (ratio of chest transverse diameter over the distance between sternum and spine), and transthoracic echocardiography implemented with 2D-speckle tracking analysis. MHI was significantly greater in MVP group than controls (2.6 ± 0.35 vs 2.1 ± 0.23, p < 0.0001). Left ventricular (LV) ejection fraction was similar in MVP and controls (63.5 ± 3.7% vs 64.3 ± 3.9%, p = 0.25). LV regional and global longitudinal (GLS), circumferential (GCS) and radial strain (GRS) parameters and LV peak twist were all significantly lower in MVP compared to controls (all p < 0.0001). MVP subjects with a tight chest (MHI > 2.5, n = 30), and those with MHI ≤ 2.5 (n = 30) were then separately analyzed. A significant impairment in myocardial strain parameters and LV peak twist was documented in MVP subjects with MHI > 2.5, but not in those with MHI ≤ 2.5. MHI showed a strong inverse correlation with LV-GLS (r = - 0.85), GCS (r = - 0.84), GRS (r = - 0.84) and LV peak twist (r = - 0.94). In MVP subjects, impairment of myocardial strain parameters is not due to intrinsic reduction of cardiac contractility function, but it appears to be related to the degree of chest deformity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.