Evidence map›Paper›PMID 33128136›Full record

SynthesisActa diabetologica2021

Efficacy, safety, and user experience of DIY or open-source artificial pancreas systems: a systematic review.

N A M Asarani, A N Reynolds, M Elbalshy, M Burnside, M de Bock, D M Lewis, B J Wheeler

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta diabetologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Review
  14. Mapping the Landscape of Do-it-Yourself Medicine.Citizen science : theory and practice · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

N A M AsaraniDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.ORCID http://orcid.org/0000-0002-4147-7492
A N ReynoldsDepartment of Medicine, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
M ElbalshyDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
M BurnsideDepartment of Paediatrics, University of Otago, Christchurch, New Zealand.
M de BockDepartment of Paediatrics, University of Otago, Christchurch, New Zealand.
D M LewisOpenAPS, Seattle, WA, 98101, USA.
B J WheelerDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin, 9054, New Zealand. ben.wheeler@otago.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The do-it-yourself artificial pancreas system (DIYAPS) is a patient-driven initiative with the potential to revolutionise diabetes management, automating insulin delivery with existing pumps and CGM combined with open-source algorithms. Given the considerable interest in this topic within the diabetes community, we have conducted a systematic review of DIYAPS efficacy, safety, and user experience. Following recognised procedures and reporting standards, we identified 10 eligible publications of 730 participants within the peer-reviewed literature. Overall, studies reported improvements in time in range, HbA1c (glycated haemoglobin), reduced hypoglycaemia, and improved quality of life with DIYAPS use. While results were positive, the identified studies were small, and the majority were observational and at high risk of bias. Further research including well-designed randomised trials comparing DIYAPS with appropriate comparators is recommended.

Indexed as

Diabetes Mellitus, Type 1Glycemic ControlPancreas, ArtificialSelf-ManagementAdultBlood Glucose Self-MonitoringGlycated HemoglobinHumansHypoglycemiaInsulinInsulin Infusion SystemsPatient SatisfactionQuality of LifeTreatment OutcomeGlycated HemoglobinInsulinArtificial pancreasDo-it-yourselfGlucose sensing technologyOpen-source

Identifiers

PMID33128136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.