ArticleEuropean journal of public health2021
Life-course risk factors are associated with activity of daily living disability in older adults.
Article in European journal of public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Impact of disability and selected factors on the quality of life in the older people in southeastern Poland - a cross-sectional study.BMC public health · 2026Article
- The "long arm of childhood" on mortality in older adulthood in the United States and Brazil: examining the role of educational attainment and differences by gender.American journal of epidemiology · 2026Article
- Increased Depressive and Anxiety Symptoms Predict Increased Severity of Functional Impairment After Five Years: A Nationally Representative Retrospective Cohort Study.Journal of patient-centered research and reviews · 2025Article
- Does a Reduction in Receiving Assistance With Daily Activities Among Older Adults in Mexico Indicate An Increase in Unmet Needs or a Decrease in Needs for Care?The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Cohort Profile: The Brazilian Longitudinal Study of Ageing (ELSI-Brazil).International journal of epidemiology · 2023Article
- Disability risk prediction model based on machine learning among Chinese healthy older adults: results from the China Health and Retirement Longitudinal Study.Frontiers in public health · 2023Article
- Subjective cognitive decline in Brazil: Prevalence and association with dementia modifiable risk factors in a population-based study.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
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Authors and funding
6 authors.
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Abstract
backgroundMultiple risk factors accumulate over the life-course and contribute to higher rates of disability at older ages. This study investigates whether three life-course risk factors (low educational attainment, poor health in childhood and multimorbidity) are associated with increased risk of disability [defined as any limitation in basic activities of daily living (BADL)] in older adults and whether this relationship is moderated by the national socioeconomic context, measured by the Human Development Index (HDI).
methodsData include 100 062 adults (aged 50 and over) participating in longitudinal studies of aging conducted in 19 countries. Analyses include multivariable Poisson models with robust standard errors to assess the associations between HDI, life-course risk factors and other individual-level control variables (sex and age) with any BADL disability.
resultsIn country-specific analyses, both educational attainment and multimorbidity are independently associated with disability in nearly every country. The interaction between these risk factors further increases the magnitude of this association. In pooled regression analyses, the relationship between life-course risk factors and disability is moderated by a country's HDI. For individuals with all three life-course risk factors, the predicted probability of disability ranged from 36.7% in the lowest HDI country to 21.8% in the highest HDI country.
conclusionsSocial and health system policies directed toward reducing the development of life-course risk factors are essential to reduce disability in all countries, but are even more urgently needed in those with lower levels of socioeconomic development.
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