ArticleScientific reports2020
Asymptomatic Plasmodium falciparum malaria prevalence among adolescents and adults in Malawi, 2015-2016.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Trial
- Prevalence of malaria and associated risk factors in Loka Abaya district, Sidama regional state, Southern Ethiopia.Malaria journal · 2026Article
- Mechanistic insights into subclinicaliScience · 2026Review
- Uncovering silent malaria reservoirs in Southern Ethiopia: community-based molecular detection of asymptomatic and sub-microscopic infections and their implications for diagnosis and control.Malaria journal · 2026Article
- Who uses the only mosquito net? Sex and age disparities.Tropical medicine and health · 2026Article
- Patterns of patent and sub-patent Plasmodium falciparum infections in household members of children under seasonal malaria chemoprevention coverage in the health district of Nanoro, Burkina Faso.Malaria journal · 2025Article
- Impact of asymptomatic malaria infection on children's growth in rural Malawi.Scientific reports · 2025Article
- Hidden reservoirs of infection: prevalence and risk factors of asymptomatic malaria in a high-endemic region of Zambia.Malaria journal · 2025Article
- Prevalence of malaria and its associated factors among adults living in Samre Woreda, Tigray, Ethiopia, 2023/24: a community-based cross-sectional study.BMC public health · 2025Article
- Exploring the prevalence and association between nutritional status and asymptomatic malaria in Rwanda among under-5 children: a cross-sectional analysis.Malaria journal · 2025Article
- Asymptomatic Plasmodium falciparum infections and determinants of carriage in a seasonal malaria chemoprevention setting in Northern Cameroon and south Senegal (Kedougou).Malaria journal · 2024Article
- Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells.International immunology · 2024Article
- Genomic insights into Plasmodium vivax population structure and diversity in central Africa.Malaria journal · 2024Article
- One Haemolytic Anaemia May Hide Another: Paroxysmal Nocturnal Haemoglobinuria Masquerading AsEuropean journal of case reports in internal medicine · 2024Article
- Temporal and spatial analysis of Plasmodium falciparum genomics reveals patterns of parasite connectivity in a low-transmission district in Southern Province, Zambia.Malaria journal · 2023Article
- Symptomatic and asymptomatic malaria prevalence and its determinant factors in pastoral communities of Waghemira Zone, Northeast Ethiopia: A community-based cross-sectional study.Health science reports · 2023Article
- Magnitude of Malaria and its Associated Factors among Febrile Patients Aged Five Years and above: A cross-sectional Study in Ngoma District, Rwanda.Rwanda journal of medicine and health sciences · 2023Article
- Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi.Malaria journal · 2023Article
- Article
- Long-lasting insecticide-treated net use and malaria infections on the Kenyan coast.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022Article
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Authors and funding
17 authors at 4 institutions in 2 countries.
Funding
Abstract
Malaria remains a significant cause of morbidity and mortality in Malawi, with an estimated 18-19% prevalence of Plasmodium falciparum in children 2-10 years in 2015-2016. While children report the highest rates of clinical disease, adults are thought to be an important reservoir to sustained transmission due to persistent asymptomatic infection. The 2015-2016 Malawi Demographic and Health Survey was a nationally representative household survey which collected dried blood spots from 15,125 asymptomatic individuals ages 15-54 between October 2015 and February 2016. We performed quantitative polymerase chain reaction on 7,393 samples, detecting an overall P. falciparum prevalence of 31.1% (SE = 1.1). Most infections (55.6%) had parasitemias ≤ 10 parasites/µL. While 66.2% of individuals lived in a household that owned a bed net, only 36.6% reported sleeping under a long-lasting insecticide-treated net (LLIN) the previous night. Protective factors included urbanicity, greater wealth, higher education, and lower environmental temperatures. Living in a household with a bed net (prevalence difference 0.02, 95% CI - 0.02 to 0.05) and sleeping under an LLIN (0.01; - 0.02 to 0.04) were not protective against infection. Our findings demonstrate a higher parasite prevalence in adults than published estimates among children. Understanding the prevalence and distribution of asymptomatic infection is essential for targeted interventions.
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