ArticleScientific reports2020
Macular vessel density and foveal avascular zone parameters in patients after acute primary angle closure determined by OCT angiography.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Long-term optic nerve head microvascular impairment after acute primary angle closure: an OCTA study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Alterations in Retinal Vasculometry After Acute Primary Angle Closure Episode: A Comparative Analysis.Translational vision science & technology · 2026Article
- Comparing structural and vascular parameters between healthy eyes and eyes with primary angle-closure disease.BMC ophthalmology · 2026Article
- Effect of Circadian Blood Pressure Variations on Retinal Microvascular Structures: Optical Coherence Tomography Angiography Analysis with the Nighttime Divided into Subintervals (Retinal Dawn Pattern).Medicina (Kaunas, Lithuania) · 2025Article
- Foveal Avascular Zone Enlargement as a Risk Factor for Early Retinal Ganglion Cell Dysfunction in Glaucoma Suspects.Diagnostics (Basel, Switzerland) · 2025Article
- Macular vascular density changes in different stages of chronic primary angle-closure glaucoma.Frontiers in medicine · 2025Article
- Alterations in Macular Microvasculature in Pterygium Patients Measured by OCT Angiography.Diagnostics (Basel, Switzerland) · 2023Article
- EFEMP1 is a potential biomarker of choroid thickness change in myopia.Frontiers in neuroscience · 2023Article
- Structural measurements and vessel density of spectral-domain optic coherence tomography in early, moderate, and severe primary angle-closure glaucoma.International journal of ophthalmology · 2023Article
- Quantitative Measurements of Vessel Density and Blood Flow Areas Primary Angle Closure Diseases: A Study of Optical Coherence Tomography Angiography.Journal of clinical medicine · 2022Article
- Optical coherence tomography angiography of the macular microcirculation in acute primary angle closure treated with phacoemulsification.International ophthalmology · 2022Article
- Spatial positional relationship between macular superficial vessel density and ganglion cell-inner plexiform layer thickness in primary angle closure glaucoma.International ophthalmology · 2022Article
- Body shape and risk of glaucoma: A Mendelian randomization.Frontiers in medicine · 2022Article
- Ocular perfusion in primary angle-closure suspect and primary angle-closure eyes without prior acute angle closure.Oman journal of ophthalmologyArticle
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study analyzed the optical coherence tomography angiography (OCTA) macular parameters in primary angle-closure glaucoma (PACG) patients after acute primary angle closure (APAC) episodes. Thirty-three patients with 33 APAC eyes and 33 primary angle closure suspect (PACS) eyes and 33 age-matched normal subjects (controls) were enrolled. Macular vessel density (VD) in central, inner, outer and full regions and foveal avascular zone (FAZ) parameters (area, perimeter and circularity index) were compared between APAC, PACS, and control eyes. For resolved APAC eyes, the VD in each macular region was significantly lower than that in control eyes, with less central and inner macular VD than PACS eyes. The central macular VD was significantly lower in PACS eyes than in controls. There was no difference in FAZ area and perimeter between APAC, PACS, and control eyes. FAZ circularity was highest in control eyes, followed by PACS eyes, and lowest in APAC eyes. The AUC, sensitivity and specificity of FAZ circularity were 0.944, 93.9% and 84.8%, respectively, in APAC eyes and 0.881, 84.8% and 81.8%, respectively, in PACS eyes. Therefore, FAZ circularity had the best discrimination capability for detecting both APAC and PACS eyes. Macular assessment with OCTA could provide an accurate early-stage diagnostic tool for PACG.
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