ArticleNature communications2020
Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 75 citations in OpenAlex.
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- Microcompartments in archaeal ancestors of eukaryotes: a bioenergetic engine that could have fuelled eukaryogenesis.bioRxiv : the preprint server for biology · 2025Article
- Phylogenomic Analyses Reveal that Panguiarchaeum Is a Clade of Genome-Reduced Asgard Archaea Within the Njordarchaeia.Molecular biology and evolution · 2025Article
- Candidatus List No. 6.International journal of systematic and evolutionary microbiology · 2025Article
- Oxidative adaptations in prokaryotes imply the oxygenic photosynthesis before crown-groupPNAS nexus · 2025Article
- Culture-supported ecophysiology of the SAR116 clade demonstrates metabolic and spatial niche partitioning.The ISME journal · 2025Article
- Metagenomic insights into microbial adaptation to the salinity gradient of a typical short residence-time estuary.Microbiome · 2024Article
- Comparative genomics of Ascetosporea gives new insight into the evolutionary basis for animal parasitism in Rhizaria.BMC biology · 2024Article
- Expanded phylogeny of extremely halophilic archaea shows multiple independent adaptations to hypersaline environments.Nature microbiology · 2024Article
- Gene inversion led to the emergence of brackish archaeal heterotrophs in the aftermath of the Cryogenian Snowball Earth.PNAS nexus · 2024Article
- Phylogenetic reconciliation: making the most of genomes to understand microbial ecology and evolution.The ISME journal · 2024Review
- Generation of secondary microbial methane of high-rank coals: insights from the microbial community and carbon isotope.Frontiers in microbiology · 2024Article
- Incongruence in the phylogenomics era.Nature reviews. Genetics · 2023Review
- Genomics of soil depth niche partitioning in the Thaumarchaeota family Gagatemarchaeaceae.Nature communications · 2023Article
- Parameter Estimation and Species Tree Rooting Using ALE and GeneRax.Genome biology and evolution · 2023Article
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- The origin and evolution of methanogenesis andPNAS nexus · 2023Article
- Gene gain facilitated endosymbiotic evolution of Chlamydiae.Nature microbiology · 2023Article
- Comparative Genomic Insights into the Evolution ofmSystems · 2022Article
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Authors and funding
7 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Halobacteria (henceforth: Haloarchaea) are predominantly aerobic halophiles that are thought to have evolved from anaerobic methanogens. This remarkable transformation most likely involved an extensive influx of bacterial genes. Whether it entailed a single massive transfer event or a gradual stream of transfers remains a matter of debate. To address this, genomes that descend from methanogen-to-halophile intermediates are necessary. Here, we present five such near-complete genomes of Marine Group IV archaea (Hikarchaeia), the closest known relatives of Haloarchaea. Their inclusion in gene tree-aware ancestral reconstructions reveals an intermediate stage that had already lost a large number of genes, including nearly all of those involved in methanogenesis and the Wood-Ljungdahl pathway. In contrast, the last Haloarchaea common ancestor gained a large number of genes and expanded its aerobic respiration and salt/UV resistance gene repertoire. Our results suggest that complex and gradual patterns of gain and loss shaped the methanogen-to-halophile transition.
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