Evidence map›Paper›PMID 33127683›Full record

ArticleScience advances2020

K

Marco Lolicato, Andrew M Natale, Fayal Abderemane-Ali, David Crottès, Sara Capponi, Ramona Duman, Armin Wagner, John M Rosenberg, Michael Grabe, Daniel L Minor

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 94 citations in OpenAlex.

  1. Similarity of the ion occupations of KChannels (Austin, Tex.) · 2026
    Article
  2. Review
  3. Gating crosstalk in potassium channels.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. KArchiv der Pharmazie · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. TREK-1 and epilepsy: regulating the balance of KBehavioral and brain functions : BBF · 2025
    Review
  13. Article
  14. Structure of the human KNature structural & molecular biology · 2025
    Article
  15. Gating mechanism of the two-pore-domain potassium channel THIK1.Nature structural & molecular biology · 2025
    Article
  16. Cryo-EM structure of the human THIK-1 K2P KNature structural & molecular biology · 2025
    Article
  17. Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Marco LolicatoCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA.ORCID 0000-0002-2022-7961
Andrew M NataleCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA.ORCID 0000-0002-6320-0216
Fayal Abderemane-AliCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA.
David CrottèsDepartment of Physiology, University of California, San Francisco, CA 93858-2330, USA.ORCID 0000-0002-4038-6345
Sara CapponiCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA.ORCID 0000-0001-8117-7526
Ramona DumanScience Division, Diamond Light Source, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK.
Armin WagnerScience Division, Diamond Light Source, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK.ORCID 0000-0001-8995-7324
John M RosenbergDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0001-7616-4376
Michael GrabeCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA. michael.grabe@ucsf.edu daniel.minor@ucsf.edu.ORCID 0000-0003-3509-5997
Daniel L MinorCardiovascular Research Institute, University of California, San Francisco, CA 93858-2330, USA. michael.grabe@ucsf.edu daniel.minor@ucsf.edu.ORCID 0000-0002-5998-4214
University of California, San Francisco · USDiamond Light Source · GBQB3 · USUniversity of Pittsburgh · US

Funding

STRUCTURAL BIOLOGY TRAINING PROGRAMT32GM008284 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KORTEMME, TANJA · 1988 to 2022
$10.1M
Genetic and chemical biological studies of K2P structure, function, andmodulationR01MH093603 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2011 to 2026
$8.5M
Breakthrough Molecular Dynamics Research via an Anton2 SupercomputerR01GM116961 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI BLOOD, PHILIP D. · 2016 to 2023
$3.0M
Computational Studies of Sodium SymportersR01GM089740 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRABE, MICHAEL · 2011 to 2020
$2.8M
High Performance Computer for Computational BiosciencesS10OD021596 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SALI, ANDREJ · 2016 to 2016
$443k
New tools for computing macro and microscopic channel properties from structureR21NS091941 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROSENBERG, JOHN M · 2015 to 2016
$440k
Computer simulations of lysosomal and osteoclast microphysiologyR21GM100224 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRABE, MICHAEL · 2012 to 2013
$403k
NIGMS NIH HHS R01 GM089740NIGMS NIH HHS R01 GM116961NIGMS NIH HHS R21 GM100224NIGMS NIH HHS T32 GM008284NIH HHS S10 OD021596NIMH NIH HHS R01 MH093603NINDS NIH HHS R21 NS091941
6 · The paper itself

Abstract

K

Identifiers

PMID33127683
PMCPMC7608817
OpenAlexW3095128957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.