ArticleScience advances2020
Viscoelastic properties of biopolymer hydrogels determined by Brillouin spectroscopy: A probe of tissue micromechanics.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 105 citations in OpenAlex.
- The mechanical properties ofScience advances · 2026Article
- Stabilized real-time Brillouin microscopy reveals fractal organization of protein condensates in living cells.Nature communications · 2026Article
- Article
- A framework for spontaneous Brillouin noise: unveiling fundamental limits in Brillouin metrology.Light, science & applications · 2026Article
- Brillouin Microscopy of Breast tumor Spheroids On-a-Chip: Mechanical and Transcriptional Responses to Microfluidic-Induced Rapid Deformations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Exploring the biomechanical complexity of glioblastoma spheroids and organoids with co-localized Brillouin and Raman microspectroscopy.Biochemistry and biophysics reports · 2025Article
- Cellular mechanical properties in response to environmental viscosity imaged by Brillouin Microscopy.Communications biology · 2025Article
- Elasticity and Dynamics of Elastomeric Epoxy Networks: Comparing Simulations and Experiments at High Frequency.ACS macro letters · 2025Article
- Imaging the mechanical properties of a developing embryonic tendon using Brillouin microscopy.Acta biomaterialia · 2025Article
- Beyond Water Content: Unraveling Stiffness in Hydrated Materials by a Correlative Brillouin-Raman Approach.ACS photonics · 2025Article
- Brillouin Spectroscopy: A Non-Invasive Method for Assessing the Viscoelastic Properties of Biologically Relevant Polymers.Journal of biomedical materials research. Part A · 2025Article
- Assessing UVA and Laser-Induced Crosslinking via Brillouin Microscopy.Journal of biophotonics · 2025Article
- Micromechanical behavior of the apple fruit cuticle investigated by Brillouin light scattering microscopy.Communications biology · 2025Article
- Fundamentals and Advances in Stimuli-Responsive Hydrogels and Their Applications: A Review.Gels (Basel, Switzerland) · 2025Review
- Multiscale Elasticity of Epoxy Networks by Rheology and Brillouin Light Spectroscopy.The journal of physical chemistry. B · 2024Article
- Optical characterization of molecular interaction strength in protein condensates.Molecular biology of the cell · 2024Article
- Article
- Optical characterization of molecular interaction strength in protein condensates.bioRxiv : the preprint server for biology · 2024Article
- A Comprehensive Review on the Viscoelastic Parameters Used for Engineering Materials, Including Soft Materials, and the Relationships between Different Damping Parameters.Sensors (Basel, Switzerland) · 2024Review
- Mechanistic divergences of endocytic clathrin-coated vesicle formation in mammals, yeasts and plants.Journal of cell science · 2024Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Many problems in mechanobiology urgently require characterization of the micromechanical properties of cells and tissues. Brillouin light scattering has been proposed as an emerging optical elastography technique to meet this need. However, the information contained in the Brillouin spectrum is still a matter of debate because of fundamental problems in understanding the role of water in biomechanics and in relating the Brillouin data to low-frequency macroscopic mechanical parameters. Here, we investigate this question using gelatin as a model system in which the macroscopic physical properties can be manipulated to mimic all the relevant biological states of matter, ranging from the liquid to the gel and the glassy phase. We demonstrate that Brillouin spectroscopy is able to reveal both the elastic and viscous properties of biopolymers that are central to the structure and function of biological tissues.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.