Evidence map›Paper›PMID 33127631›Full record

SynthesisBMJ open2020

DECAF score as a mortality predictor for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Qiangru Huang, Chengying He, Huaiyu Xiong, Tiankui Shuai, Chuchu Zhang, Meng Zhang, Yalei Wang, Lei Zhu, Jiaju Lu, Liu Jian

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Qiangru HuangICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Chengying HeICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Huaiyu XiongICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Tiankui ShuaiICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Chuchu ZhangICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Meng ZhangICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Yalei WangICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Lei ZhuICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Jiaju LuICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China.
Liu JianICU, Lanzhou University First Affiliated Hospital, Lanzhou, Gansu, China medecinliu@sina.com.ORCID 0000-0002-1825-571X
First Hospital of Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study was conducted to assess the association between the Dyspnea, Eosinopenia, Consolidation, Acidemia and Atrial Fibrillation (DECAF) scores and the prognosis of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), to evaluate the specific predictive and prognostic value of DECAF scores and to explore the effectiveness of different cut-off values in risk stratification of patients with AECOPD.

designSystematic review and meta-analysis.

participantsAdult patients diagnosed with AECOPD (over 18 years of age). PRIMARY AND SECONDARY OUTCOME MEASURES: Electronic databases, including the Cochrane Library, PubMed, the Embase and the WOS, and the reference lists in related articles were searched for studies published up to September 2019. The identified studies reported the prognostic value of DECAF scores in patients with AECOPD.

resultsSeventeen studies involving 8329 participants were included in the study. Quantitative analysis demonstrated that elevated DECAF scores were associated with high mortality risk (weighted mean difference=1.87; 95% CI 1.19 to 2.56). In the accuracy analysis, DECAF scores showed good prognostic accuracy for both in-hospital and 30-day mortality (area under the receiver operating characteristic curve: 0.83 (0.79-0.86) and 0.79 (0.76-0.83), respectively). When the prognostic value was compared with that of other scoring systems, DECAF scores showed better prognostic accuracy and stable clinical values than the modified DECAF; COPD and Asthma Physiology Score; BUN, Altered mental status, Pulse and age >65; Confusion, Urea, Respiratory Rate, Blood pressure and age >65; or Acute Physiology and Chronic Health Evaluation II scores.

conclusionThe DECAF score is an effective and feasible predictor for short-term mortality. As a specific and easily scored predictor for patients with AECOPD, DECAF score is superior to other prognostic scores. The DECAF score can correctly identify most patients with AECOPD as low risk, and with the increase of cut-off value, the risk stratification of DECAF score in high-risk population increases significantly.

Indexed as

Pulmonary Disease, Chronic ObstructiveAdolescentAdultDisease ProgressionHospital MortalityHumansPredictive Value of TestsROC Curveadult intensive & critical carechronic airways diseaserespiratory medicine (see thoracic medicine)

Identifiers

PMID33127631
PMCPMC7604856
OpenAlexW3096589100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.