ArticleBMJ open2020
Study protocol for a prospective, longitudinal cohort study investigating the medical and psychosocial outcomes of UK combat casualties from the Afghanistan war: the ADVANCE Study.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07766447 (Long-term Medical Impact of War Injuries on Military Personnel), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-term Medical Impact of War Injuries on Military Personnel
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between non-acute Traumatic Injury (TI) and Heart Rate Variability (HRV) in adults: A systematic review and meta-analysis.PloS one · 2023Pooled it
- A Scoping Review on Bone Mass Status in Individuals with Transfemoral Amputation.Journal of prosthetics and orthotics : JPO · 2026Review
- Combat Injury, Limb Loss, Traumatic Brain Injury, and Psychosocial Outcomes Among Military Personnel.JAMA network open · 2026Article
- Novel Musculoskeletal Hypotheses in the Armed Services Trauma and Rehabilitation Outcome (ADVANCE) Cohort: Development and Application of Sparse Group Factor Analysis Methodology.Journal of medical Internet research · 2026Article
- Deployment-related wound infection surveillance for military casualties: a transatlantic collaboration.BMJ military health · 2026Article
- Understanding long-term physical and psychosocial outcomes from conflict to rehabilitation through the ADVANCE cohort.Communications medicine · 2026Review
- Biases in the measurement of health-related quality of life in the EQ-5D-5L among those with serious physical traumatic injuries: the ADVANCE cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Influence of major trauma and lower limb loss on radiographic progression and incidence of knee osteoarthritis and pain: a comparative and predictive analysis from the ADVANCE study.Arthritis research & therapy · 2026Article
- Relationships between combat injury, pain, mobility and post-service employment: the ADVANCE study.Occupational and environmental medicine · 2026Article
- Article
- Prevalence, incidence, and progression of hip osteoarthritis in a young military population: The ADVANCE cohort study.Osteoarthritis and cartilage open · 2025Article
- Insights into knee post-traumatic osteoarthritis pathophysiology from the relationship of serum biomarkers to radiographic features in the ADVANCE cohort.Arthritis research & therapy · 2025Article
- Evaluating the physical and psychosocial impact of serious physical combat injuries in UK armed forces personnel-the ADVANCE cohort study.European journal of epidemiology · 2025Article
- The underlying mechanisms by which Post-Traumatic Growth is associated with cardiovascular health in male UK military personnel: The ADVANCE cohort study.Journal of health psychology · 2025Article
- How can Blood Flow Restriction Exercise be Utilised for the Management of Persistent Pain Following Complex Injuries in Military Personnel? A Narrative Review.Sports medicine - open · 2025Review
- Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: the ADVANCE study.Journal of neurology, neurosurgery, and psychiatry · 2025Article
- Observational
- Osteoarthritis after major combat trauma: the Armed Services Trauma Rehabilitation Outcome Study.Rheumatology advances in practice · 2025Article
- Relationship between combat-related traumatic injury and ultrashort term heart rate variability in a UK military cohort: findings from the ADVANCE study.BMJ military health · 2024Article
- Validity of Ultra-Short-Term Heart Rate Variability Derived from Femoral Arterial Pulse Waveform in a British Military Cohort.Applied psychophysiology and biofeedback · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe Afghanistan war (2003-2014) was a unique period in military medicine. Many service personnel survived injuries of a severity that would have been fatal at any other time in history; the long-term health outcomes of such injuries are unknown. The METHODS AND ANALYSIS: ADVANCE is a prospective cohort study. 1200 Afghanistan-deployed male UK military personnel and veterans will be recruited and will be studied at 0, 3, 6, 10, 15 and 20 years. Half are personnel who sustained combat trauma; a comparison group of the same size has been frequency matched based on deployment to Afghanistan, age, sex, service, rank and role. Participants undergo a series of physical health tests and questionnaires through which information is collected on cardiovascular disease (CVD), CVD risk factors, musculoskeletal disease, mental health, functional and social outcomes, quality of life, employment and mortality. ETHICS AND DISSEMINATION: The ADVANCE Study has approval from the Ministry of Defence Research Ethics Committee (protocol no:357/PPE/12) agreed 15 January 2013. Its results will be disseminated through manuscripts in clinical/academic journals and presentations at professional conferences, and through participant and stakeholder communications. TRIAL REGISTRATION NUMBER: The ADVANCE Study is registered at ISRCTN ID: ISRCTN57285353.
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