Evidence map›Paper›PMID 33127625›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Feasibility of Single-Time-Point Dosimetry for Radiopharmaceutical Therapies.

Xinchi Hou, Julia Brosch, Carlos Uribe, Alessandro Desy, Guido Böning, Jean-Mathieu Beauregard, Anna Celler, Arman Rahmim

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 72 citations in OpenAlex.

  1. Outcome-driven dosimetry optimization for [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Dosimetry inJournal of clinical medicine · 2026
    Review
  4. OptimizingNuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Fast [EJNMMI physics · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. CanJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  11. Characterization of Effective Half-Life for Instant Single-Time-Point Dosimetry Using Machine Learning.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Impact of Posttreatment SPECT/CT on Patient Management DuringJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  16. Impact of the Reference Multiple-Time-Point Dosimetry Protocol on the Validity of Single-Time-Point Dosimetry for [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  17. Estimation of kidney doses from [EJNMMI physics · 2024
    Article
  18. Review
  19. Article
  20. Assessing Response to PSMA Radiopharmaceutical Therapies with Single SPECT Imaging at 24 Hours After Injection.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xinchi HouDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; arman.rahmim@ubc.ca.
Julia BroschDepartment of Nuclear Medicine, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany.
Carlos UribeDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.
Alessandro DesyCancer Research Centre and Department of Radiology and Nuclear Medicine, Université Laval, Quebec City, Quebec, Canada.
Guido BöningDepartment of Nuclear Medicine, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany.
Jean-Mathieu BeauregardCancer Research Centre and Department of Radiology and Nuclear Medicine, Université Laval, Quebec City, Quebec, Canada.
Anna CellerDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.
Arman RahmimDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; arman.rahmim@ubc.ca.
University of British Columbia · CALudwig-Maximilians-Universität München · DEUniversité Laval · CA

Funding

CIHR MOP-142233
6 · The paper itself

Abstract

Because of challenges in performing routine personalized dosimetry in radiopharmaceutical therapies, interest in single-time-point (STP) dosimetry, particularly using only a single SPECT scan, is on the rise. Meanwhile, there are questions about the reliability of STP dosimetry, with limited independent validations. In the present work, we analyzed 2 STP dosimetry methods and evaluated dose errors for several radiopharmaceuticals based on effective half-life distributions.

Indexed as

Feasibility StudiesNeuroendocrine TumorsRadiometryRadiopharmaceuticalsHalf-LifeHumansMaleProstatic NeoplasmsReproducibility of ResultsTime FactorsTomography, Emission-Computed, Single-PhotonRadiopharmaceuticalsdosimetryquantitationradiopharmaceutical therapysingle-time-pointSPECT

Identifiers

PMID33127625
PMCPMC8882881
OpenAlexW3096049656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.