Evidence map›Paper›PMID 33127624›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Intraprostatic Tumor Segmentation on PSMA PET Images in Patients with Primary Prostate Cancer with a Convolutional Neural Network.

Dejan Kostyszyn, Tobias Fechter, Nico Bartl, Anca L Grosu, Christian Gratzke, August Sigle, Michael Mix, Juri Ruf, Thomas F Fassbender, Selina Kiefer and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Molecular Imaging in Photon Radiotherapy.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  6. Review
  7. Review
  8. The Role of Artificial Intelligence in Theranostics.Journal of nuclear medicine technology · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Update on PSMA-based Prostate Cancer Imaging.Seminars in nuclear medicine · 2024
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 6 institutions in 2 countries.

Dejan KostyszynDivision of Medical Physics, Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Tobias FechterDivision of Medical Physics, Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nico BartlGerman Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Anca L GrosuGerman Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Christian GratzkeDepartment of Urology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
August SigleDepartment of Urology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Michael MixDepartment of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Juri RufDepartment of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Thomas F FassbenderDepartment of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Selina KieferInstitute for Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Alisa S BettermannDepartment of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nils H NicolayGerman Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Simon SpohnGerman Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Maria U KramerDepartment of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Peter BronsertGerman Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Hongqian GuoDepartment of Urology, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.
Xuefeng QiuDepartment of Urology, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.
Feng WangDepartment of Nuclear Medicine, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.
Christoph HenkenberensDepartment of Radiation Oncology, Hannover Medical School, Hannover, Germany.
Rudolf A WernerDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Dimos BaltasDivision of Medical Physics, Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Philipp T MeyerDepartment of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Thorsten DerlinDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Mengxia ChenDepartment of Urology, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.
Constantinos ZamboglouGerman Cancer Consortium (DKTK), Partner Site Freiburg, Germany constantinos.zamboglou@uniklinik-freiburg.de.
University of Freiburg · DENanjing Drum Tower Hospital · CNUniversity Medical Center Freiburg · DEDeutschen Konsortium für Translationale Krebsforschung · DEMedizinische Hochschule Hannover · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate delineation of the intraprostatic gross tumor volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen PET (PSMA PET) may outperform MRI in GTV detection. However, visual GTV delineation underlies interobserver heterogeneity and is time consuming. The aim of this study was to develop a convolutional neural network (CNN) for automated segmentation of intraprostatic tumor (GTV-CNN) in PSMA PET.

Indexed as

Gallium IsotopesGallium RadioisotopesNeural Networks, ComputerPositron-Emission TomographyCohort StudiesHumansImage Processing, Computer-AssistedMaleProstatic NeoplasmsTumor Burdengallium 68 PSMA-11Gallium IsotopesGallium Radioisotopesconvolutional neuronal networkshistopathologyprostate cancerPSMA-PETsegmentation

Identifiers

PMID33127624
PMCPMC8729869
OpenAlexW3096454384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.