ReviewBest practice & research. Clinical obstetrics & gynaecology2021
Surgery including fertility-sparing treatment of GTD.
Review in Best practice & research. Clinical obstetrics & gynaecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Electrochemical biosensors: a novel approach for rapid and cost-effective hCG monitoring in gestational trophoblastic tumours.RSC advances · 2026Review
- Choriocarcinoma at an Abdominal Wall Cesarean Scar: Recurrence After Multi-Line Chemotherapy and Exploration of Salvage Therapy.International journal of women's health · 2026Article
- Severe hemorrhage in choriocarcinoma: three scenarios and treatment strategies.Gynecologic oncology reports · 2025Article
- Molar Pregnancy: Early Diagnosis, Clinical Management, and the Role of Referral Centers.Diagnostics (Basel, Switzerland) · 2025Review
- Uterus-Preserving Management of Intractable Haemorrhage Following Suction and Evacuation: A Case Series.Cureus · 2025Article
- Analysis of Fertility Prognosis and Risk Factors in Patients Post-Gestational Trophoblastic Disease.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Clinical features and demographic characteristics of gestational trophoblastic neoplasia: Single center experience and the SEER database.Biomolecules & biomedicine · 2024Article
- The fertility-sparing treatment and outcome of epithelioid trophoblastic tumor isolated to lung: a case report and review literature.Frontiers in oncology · 2024Article
- Progress of immunotherapies in gestational trophoblastic neoplasms.Journal of cancer research and clinical oncology · 2023Review
- The tumor or inflammation? a case report on primary pulmonary choriocarcinoma.Frontiers in oncology · 2023Article
- Management and Predictors of Treatment Failure in Patients with Chemo-Resistant/Relapsed Gestational Trophoblastic Neoplasia with Lung Metastasis.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gestational trophoblastic disease (GTD) consists of a spectrum of diseases, including hydatidiform moles, invasive mole, metastatic mole, choriocarcinoma, placental site trophoblastic tumour (PSTT) and epithelioid trophoblastic tumour (ETT). GTD is a relatively uncommon disease occurring in women of reproductive age, with high cure rates. Primary treatment of hydatidiform moles includes uterine evacuation, followed by close monitoring of serial hCG levels to detect for post-molar gestational trophoblastic neoplasia (GTN). In patients with GTN, the main therapy consists of chemotherapy, although some surgical procedures are important in selected patients to achieve curing. Hysterectomy is the mainstay treatment for PSTT or ETT and may be considered in selected patients for management of hydatidiform mole and malignant GTN especially in chemoresistant disease. Resection of metastatic lesions such as in the lung or brain can be considered in selected patients with isolated chemoresistant tumour. Surgical treatment of GTD will be discussed in this chapter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.