Evidence map›Paper›PMID 33126934›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2020

Treatment outcomes in patients with drug-resistant TB-HIV co-infection treated with bedaquiline and linezolid.

N Padayatchi, N Bionghi, F Osman, N Naidu, N Ndjeka, I Master, J C M Brust, K Naidoo, A Ramjee, M O Donnell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  13. Favourable outcomes in RR-TB patients using BPaL and other WHO-recommended second-line anti-TB drugs.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

N PadayatchiCentre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, College of Health Sciences, Medical Research Council-Centre for the AIDS Program of Research in South Africa HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Congella, South Africa.
N BionghiColumbia University College of Physicians and Surgeons, New York, NY, USA.
F OsmanCentre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, College of Health Sciences, Medical Research Council-Centre for the AIDS Program of Research in South Africa HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Congella, South Africa.
N NaiduCentre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, College of Health Sciences, Medical Research Council-Centre for the AIDS Program of Research in South Africa HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Congella, South Africa.
N NdjekaNational TB Programme, South African National Department of Health, Pretoria.
I MasterKing DinuZulu Medical Complex, Sydenham, South Africa.
J C M BrustDivisions of General Internal Medicine and Infectious Diseases, Albert Einstein College of Medicine & Montefiore Medical Center, Bronx, NY.
K NaidooCentre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, College of Health Sciences, Medical Research Council-Centre for the AIDS Program of Research in South Africa HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Congella, South Africa.
A RamjeeCentre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, College of Health Sciences, Medical Research Council-Centre for the AIDS Program of Research in South Africa HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Congella, South Africa.
M O DonnellCentre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, College of Health Sciences, Medical Research Council-Centre for the AIDS Program of Research in South Africa HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Congella, South Africa, Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York, NY, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.

Funding

Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HARRIS GOLDSTEIN · 2017 to 2026
$28.3M
Novel Reporter Phages to Detect Complex TB Drug Resistance and PersistenceR01AI114900 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Michelle H Larsen, Max O'Donnell · 2015 to 2026
$7.2M
Safety, pharmacokinetics, and resistance to bedaquiline in XDR TB and HIVR01AI114304 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BRUST, JAMES C M · 2015 to 2019
$3.7M
Promoting Engagement in the Drug Resistant TB/HIV Care Continuum in South AfricaR01AI124413 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI O'DONNELL, MAX, PADAYATCHI, NESRI · 2016 to 2020
$2.7M
NIAID NIH HHS P30 AI124414NIAID NIH HHS R01 AI114304NIAID NIH HHS R01 AI114900NIAID NIH HHS R01 AI124413
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CoinfectionHIV InfectionsTuberculosis, Multidrug-ResistantAdultAntitubercular AgentsDiarylquinolinesFemaleHumansLinezolidMaleRetrospective StudiesSouth AfricaTreatment OutcomeAntitubercular AgentsbedaquilineDiarylquinolinesLinezolid

Identifiers

PMID33126934
PMCPMC8141513

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.