Evidence map›Paper›PMID 33126884›Full record

ArticleAnnals of clinical microbiology and antimicrobials2020

Severe vivax malaria trends in the last two years: a study from a tertiary care centre, Delhi, India.

Monika Matlani, Loick P Kojom, Neelangi Mishra, Vinita Dogra, Vineeta Singh

Abstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Symmetrical Peripheral Gangrene Associated withSultan Qaboos University medical journal · 2025
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  10. Clinical spectrum and complications ofMalariaWorld journal · 2025
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  16. Magnitude and patterns of severeFrontiers in medicine · 2023
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monika MatlaniDepartment of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Loick P KojomCell Biology Laboratory and Malaria Parasite Bank, ICMR-National Institute of Malaria Research, New Delhi, India.
Neelangi MishraDepartment of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Vinita DograDepartment of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Vineeta SinghCell Biology Laboratory and Malaria Parasite Bank, ICMR-National Institute of Malaria Research, New Delhi, India. vineetas_2000@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlasmodium vivax, once considered benign species, is recently being recognised to be causing severe malaria like Plasmodium falciparum. In the present study, the authors report the trends in malaria severity in P. vivax among patients from a Delhi government hospital. The aim of the study was to understand the disease severity and the burden of severe vivax malaria.

methodsA hospital based study was carried out from June 2017 to December 2018 at a tertiary care centre from Delhi, India. Patients were tested for malaria using peripheral blood smear (PBS) and/or rapid malaria antigen test (RMAT). The severe and non-severe vivax malaria categorization was done as per the WHO guidelines. Sociodemographic, clinic and paraclinical data were collected from patients and their medical records.

resultsOf the 205 patients, 177 (86.3%) had P. vivax infection, 22 (10.7%) had P. falciparum infection and six (2.9%) had mixed infection with both the species. Out of 177 P. vivax cases included in this study one or more manifestations of severe malaria was found in 58 cases (32.7%). Severe anaemia (56.9%), jaundice (15%) and significant bleeding (15%) were the most common complications reported in most of patients, along with thrombocytopenia.

conclusionsIn this study, it is evident that vivax malaria is emerging as the new severe disease in malaria patients, a significant shift in the paradigm of P. vivax pathogenesis. The spectrum of complications and alterations in the laboratory parameters in P. vivax clinical cases also indicate the recent shift in the disease severity.

Indexed as

AdolescentAdultBloodChildChild, PreschoolFemaleHumansIndiaMalaria, VivaxMaleMiddle AgedPlasmodium vivaxSeverity of Illness IndexTertiary Care CentersYoung AdultClinical trendsDisease severityIndiaPlasmodium vivaxVivax malaria

Identifiers

PMID33126884
PMCPMC7602347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.