Evidence map›Paper›PMID 33126879›Full record

ArticleBMC surgery2020

A retrospective case series of Fournier's gangrene: necrotizing fasciitis in perineum and perianal region.

Nan Zhang, Xin Yu, Kai Zhang, Tongjun Liu

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  8. Fournier's Gangrene in Neonates: A Case Report and Literature Review.Journal of plastic and reconstructive surgery · 2025
    Article
  9. Article
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  11. Modern Management of Fournier's Gangrene.Current urology reports · 2025
    Review
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  16. Article
  17. Fournier's gangrene in a female: A case report.SAGE open medical case reports · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nan ZhangGeneral Surgery, Jilin University Second Hospital, No 218 ZiQiang Street, Changchun, 130000, China.
Xin YuDepartment of Pediatrics, Jilin University First Hospital, No 71 Xinmin Street, Changchun, China.
Kai ZhangGeneral Surgery, Jilin University Second Hospital, No 218 ZiQiang Street, Changchun, 130000, China.
Tongjun LiuGeneral Surgery, Jilin University Second Hospital, No 218 ZiQiang Street, Changchun, 130000, China. tongjunliu@sina.cn.ORCID http://orcid.org/0000-0003-0887-7723
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe the clinical characteristics and management for Fournier's gangrene. Experience summary and literature references are provided for future treatment improvement.

methodsWe retrospectively reviewed the cases diagnosed with Fournier's gangrene in our department from June 2016 to June 2019. Clinical data, including manifestation, diagnosis, treatment and outcomes for Fournier's gangrene were presented.

resultsThere were 12 patients enrolled in this paper, with the average age of 60 years old. It showed a male predominance with male-to-female ratio of 6:1. The average of laboratory risk indicator for necrotizing fasciitis (LRINEC) score was 10.1. Diabetes mellitus was the main predisposing disease. 11 patients received emergency debridement and 1 patient died of sepsis on the 2nd day after admission. The mortality rate was 8.3%. 6 cases developed complications, including sepsis, pneumonia, renal and heart failure. Negative pressure wound therapy (NPWT) was applied in 10 cases, while the rest 1 received normal daily dressing changes because of fecal contamination. Flaps were utilized in 2 patients to cover the defect, including one with advancement flap and one with pudendal-thigh flap, while others received secondary suture, secondary healing, skin graft or combined management. No relapse was observed during the follow-up visits.

conclusionsFournier's gangrene is a life-threatening infection that requires early diagnosis and surgery intervention. The predisposing disease, clinical manifestation and LRINEC score should be taken into comprehensive consideration, which is helpful for timely diagnosis. Moreover, further successful treatment depends on the aggressive debridement, broad-spectrum antibiotics therapy, wound management and closure choice.

Indexed as

Fasciitis, NecrotizingFournier GangreneAgedChinaDebridementEscherichia coliFemaleHumansMaleMiddle AgedPerineumRetrospective StudiesStaphylococcus aureusFournier’s gangreneInfectionNecrotizing fasciitis

Identifiers

PMID33126879
PMCPMC7602356
OpenAlexW3097490538

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.