Evidence map›Paper›PMID 33126753›Full record

ArticleInternational journal of molecular sciences2020

B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats.

Louisa Steines, Helen Poth, Marlene Herrmann, Antonia Schuster, Bernhard Banas, Tobias Bergler

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Kidney Inflammation, Injury and Regeneration 2020.International journal of molecular sciences · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Louisa SteinesDepartment of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.ORCID 0000-0002-6027-2986
Helen PothDepartment of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.
Marlene HerrmannDepartment of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.
Antonia SchusterDepartment of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.
Bernhard BanasDepartment of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.ORCID 0000-0003-2076-2195
Tobias BerglerDepartment of Nephrology, University Hospital Regensburg, 93042 Regensburg, Germany.ORCID 0000-0002-3875-6730
University Hospital Regensburg · DE

Funding

Deutsche Forschungsgemeinschaft project number 387509280, SFB 1350 Project B6 to BT and BB
6 · The paper itself

Abstract

Intra-renal tertiary lymphoid organs (TLOs) are associated with worsened outcome in kidney transplantation (Ktx). We used an anti-BAFF (B cell activating factor) intervention to investigate whether BAFF is required for TLO formation in a full MHC-mismatch Ktx model in rats. Rats received either therapeutic immunosuppression (no rejection, NR) or subtherapeutic immunosuppression (chronic rejection, CR) and were sacrificed on d56. One group additionally received an anti-BAFF antibody (CR + AB). Intra-renal T (CD3

Indexed as

AnimalsAntibodies, MonoclonalB-Cell Activating FactorB-LymphocytesGraft RejectionKidneyKidney TransplantationLymphoid TissueMaleRatsRats, Inbred BNT-LymphocytesAntibodies, MonoclonalB-Cell Activating FactorBAFFB cellskidney transplantationtertiary lymphoid organs

Identifiers

PMID33126753
PMCPMC7662293
OpenAlexW3097076870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.