Evidence map›Paper›PMID 33126528›Full record

ArticleMarine drugs2020

Enzyme Bioprospection of Marine-Derived Actinobacteria from the Chilean Coast and New Insight in the Mechanism of Keratin Degradation in

Valentina González, María José Vargas-Straube, Walter O Beys-da-Silva, Lucélia Santi, Pedro Valencia, Fabrizio Beltrametti, Beatriz Cámara

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Microorganisms · 2023
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Valentina GonzálezLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química y Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, Valparaíso 2340000, Chile.
María José Vargas-StraubeLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química y Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, Valparaíso 2340000, Chile.
Walter O Beys-da-SilvaFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil.ORCID 0000-0001-8329-7839
Lucélia SantiFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil.ORCID 0000-0002-5698-7006
Pedro ValenciaLaboratorio de Biocatálisis y Procesamiento de Alimentos, Departamento de Ingeniería Química y Ambiental, Universidad Técnica Federico Santa María, Valparaíso 2340000, Chile.ORCID 0000-0003-2422-1548
Fabrizio BeltramettiBioC-CheM Solutions S.r.l., 21040 Gerenzano, Italy.ORCID 0000-0002-4464-3222
Beatriz CámaraLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química y Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, Valparaíso 2340000, Chile.
Federico Santa María Technical University · CLUniversidade Federal do Rio Grande do Sul · BR

Funding

An implementation science approach to address multi-level barriers to cancer screening among women living with HIV in South AfricaR21TW011715 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHIBWESHA, CARLA J · 2020 to 2021
$327k
Comisión Nacional de Investigación Científica y Tecnológica Fondecyt 1171555Comisión Nacional de Investigación Científica y Tecnológica PhD fellowship N° 21161188Comisión Nacional de Investigación Científica y Tecnológica PIA ACT172128
6 · The paper itself

Abstract

Marine actinobacteria are viewed as a promising source of enzymes with potential technological applications. They contribute to the turnover of complex biopolymers, such as pectin, lignocellulose, chitin, and keratin, being able to secrete a wide variety of extracellular enzymes. Among these, keratinases are a valuable alternative for recycling keratin-rich waste, which is generated in large quantities by the poultry industry. In this work, we explored the biocatalytic potential of 75 marine-derived actinobacterial strains, focusing mainly on the search for keratinases. A major part of the strains secreted industrially important enzymes, such as proteases, lipases, cellulases, amylases, and keratinases. Among these, we identified two streptomycete strains that presented great potential for recycling keratin wastes-

Indexed as

BioprospectingActinobacteriaBacterial ProteinsChileEnzyme StabilityHydrogen-Ion ConcentrationKeratinsPeptide HydrolasesProteolysisSubstrate SpecificityTemperatureTime FactorsBacterial ProteinskeratinaseKeratinsPeptide Hydrolaseshydrolytic enzymeskeratinolytic proteasesmarine actinobacteriarare actinobacteriasecretomeStreptomyces

Identifiers

PMID33126528
PMCPMC7693968
OpenAlexW3095959138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.