Evidence map›Paper›PMID 33126486›Full record

ArticleCells2020

Comprehensive Exonic Sequencing of Hemiplegic Migraine-Related Genes in a Cohort of Suspected Probands Identifies Known and Potential Pathogenic Variants.

Heidi G Sutherland, Neven Maksemous, Cassie L Albury, Omar Ibrahim, Robert A Smith, Rod A Lea, Larisa M Haupt, Bronwyn Jenkins, Benjamin Tsang, Lyn R Griffiths

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Hemiplegic migraine: genetics and pathophysiology.The Journal of clinical investigation · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Neurology. Genetics · 2023
    Article
  13. Genetics of migraine: where are we now?The journal of headache and pain · 2023
    Review
  14. Investigation ofFrontiers in molecular neuroscience · 2022
    Article
  15. Exploring the Hereditary Nature of Migraine.Neuropsychiatric disease and treatment · 2021
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Heidi G SutherlandCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.ORCID 0000-0002-8512-1498
Neven MaksemousCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.ORCID 0000-0002-4891-4333
Cassie L AlburyCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.
Omar IbrahimCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.
Robert A SmithCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.
Rod A LeaCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.
Larisa M HauptCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.ORCID 0000-0002-7735-8110
Bronwyn JenkinsThe Epping Clinic, Sydney, NSW 2121, Australia.
Benjamin TsangDepartment of Neurology, Sunshine Coast University Hospital, Birtinya, QLD 4575, Australia.ORCID 0000-0002-3887-6900
Lyn R GriffithsCentre for Genomics and Personalised Health, Genomics Research Centre, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.ORCID 0000-0002-6774-5475
Queensland University of Technology · AUSunshine Coast University Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemiplegic migraine (HM) is a rare migraine disorder with aura subtype including temporary weakness and visual, sensory, and/or speech symptoms. To date, three main genes-

Indexed as

Sequence Analysis, DNABase SequenceCohort StudiesExome SequencingExonsHemiplegiaHumansMembrane ProteinsMigraine DisordersMutationNerve Tissue ProteinsPrevalenceMembrane ProteinsNerve Tissue ProteinsPRRT2 protein, humanfamilial hemiplegic migraineion channel genesmigrainemutationsparoxysmal movement disordersvariantswhole exome sequencing

Identifiers

PMID33126486
PMCPMC7693486
OpenAlexW3097194550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.