Evidence map›Paper›PMID 33126483›Full record

ReviewAntioxidants (Basel, Switzerland)2020

Impacts of Green Tea on Joint and Skeletal Muscle Health: Prospects of Translational Nutrition.

Hui-Ying Luk, Casey Appell, Ming-Chien Chyu, Chung-Hwan Chen, Chien-Yuan Wang, Rong-Sen Yang, Chwan-Li Shen

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Hui-Ying LukDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX 79409, USA.
Casey AppellDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX 79409, USA.
Ming-Chien ChyuCenter of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Chung-Hwan ChenDepartment of Orthopedics and Orthopedic Research Center, Kaohsiung Municipal Ta-Tung Hospital and Kaohsiung Medical University Hospital, College of Medicine, Regeneration Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 800, Taiwan.ORCID 0000-0001-8941-4792
Chien-Yuan WangDepartment of Orthopedics, China Medical University Hsinchu Hospital, Zhubei City, Hsinchu 302, Taiwan.ORCID 0000-0002-3824-8357
Rong-Sen YangDepartment of Orthopedics, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0002-0553-4779
Chwan-Li ShenCenter of Excellence for Integrative Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Texas Tech University · USChina Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis and sarcopenia are two major joint and skeletal muscle diseases prevalent during aging. Osteoarthritis is a multifactorial progressive degenerative and inflammatory disorder of articular cartilage. Cartilage protection and pain management are the two most important strategies in the management of osteoarthritis. Sarcopenia, a condition of loss of muscle mass and strength, is associated with impaired neuromuscular innervation, the transition of skeletal muscle fiber type, and reduced muscle regenerative capacity. Management of sarcopenia requires addressing both skeletal muscle quantity and quality. Emerging evidence suggests that green tea catechins play an important role in maintaining healthy joints and skeletal muscle. This review covers (i) the prevalence and etiology of osteoarthritis and sarcopenia, such as excessive inflammation and oxidative stress, mitochondrial dysfunction, and reduced autophagy; (ii) the effects of green tea catechins on joint health by downregulating inflammatory signaling mediators, upregulating anabolic mediators, and modulating miRNAs expression, resulting in reduced chondrocyte death, collagen degradation, and cartilage protection; (iii) the effects of green tea catechins on skeletal muscle health via maintaining a dynamic balance between protein synthesis and degradation and boosting the synthesis of mitochondrial energy metabolism, resulting in favorable muscle homeostasis and mitigation of muscle atrophy with aging; and (iv) the current study limitations and future research directions.

Indexed as

agingantioxidantautophagygreen tea extractinflammationmitochondriaosteoarthritissarcopenia

Identifiers

PMID33126483
PMCPMC7692648
OpenAlexW3097382226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.