Evidence map›Paper›PMID 33126430›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome.

Anita Bálint, Klaudia Farkas, Orsolya Méhi, Bálint Kintses, Bálint Márk Vásárhelyi, Eszter Ari, Csaba Pál, Tamara Madácsy, József Maléth, Kata Judit Szántó and 10 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Anita BálintDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-3624-896X
Klaudia FarkasDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Orsolya MéhiSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, 6726 Szeged, Hungary.
Bálint KintsesSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, 6726 Szeged, Hungary.
Bálint Márk VásárhelyiSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, 6726 Szeged, Hungary.ORCID 0000-0003-1782-8691
Eszter AriSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, 6726 Szeged, Hungary.ORCID 0000-0001-7774-1067
Csaba PálSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, 6726 Szeged, Hungary.
Tamara MadácsyDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0001-5598-9723
József MaléthDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0001-5768-3090
Kata Judit SzántóDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
István NagySequencing Platform, Institute of Biochemistry, Biological Research Centre, 6726 Szeged, Hungary.ORCID 0000-0003-2528-9173
Mariann RutkaDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Péter BacsurDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-8534-0068
Diána SzűcsDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Zoltán SzepesDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Ferenc NagyDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Anna FábiánDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Renáta BorDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Ágnes MilassinDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
Tamás MolnárDepartment of Medicine, University of Szeged, 6720 Szeged, Hungary.
University of Szeged · HUHUN-REN Szegedi Biológiai Kutatóközpont · HUEötvös Loránd University · HU

Funding

Janos Bolyai Research Grant BO/00598/19/5Nemzeti Kutatási Fejlesztési és Innovációs Hivatal 125377Nemzeti Kutatási Fejlesztési és Innovációs Hivatal 129266New National Excellence Program of the Ministry of Human Capacities UNKP-19-4-SZTE-44Research Foundation of University of Szeged Hetényi Géza Research Grant 5S576Research Foundation of University of Szeged Hetényi Géza Research Grant 5S581Research Foundation of University of Szeged Hetényi Géza Research Grant 5S583University of Szeged, Open Access Fund 4938
6 · The paper itself

Abstract

Gut microbial composition alters in some special situations, such as in ulcerative colits (UC) after total proctocolectomy and ileal pouch-anal anastomosis (IPAA) surgery. The aim of our study was to determine the composition of the intestinal microbiome in UC patients after IPAA surgery, compared with UC patients, familial adenomatous polyposis (FAP) patients after IPAA surgery and healthy controls. Clinical data of patients, blood and faecal samples were collected. Faecal microbiota structure was determined by sequencing the V4 hypervariable region of the 16S rRNA gene. Overall, 56 patients were enrolled. Compared to the Healthy group, both the Pouch active and UC active groups had higher

Indexed as

faecal microbiomefamilial adenomatous polyposisfunctional anatomical changesgut microbiomepouchulcerative colitis

Identifiers

PMID33126430
PMCPMC7692875
OpenAlexW3097304687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.