Evidence map›Paper›PMID 33125887›Full record

ArticleCell2020

When Gut Microbiota Creep into Fat, the Fat Creeps Back.

Sean P Spencer, Justin L Sonnenburg

Abstract readComment
In one paragraph

Article in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. High-fat diet aggravates colitisWorld journal of gastroenterology · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sean P SpencerDivision of Gastroenterology and Hepatology, Stanford School of Medicine, Stanford, CA, USA; Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, USA. Electronic address: seanspen@stanford.edu.
Justin L SonnenburgMicrobiology & Immunology, Stanford School of Medicine, Stanford, CA, USA; Center for Human Microbiome Studies, Stanford School of Medicine, Stanford, CA, USA. Electronic address: jsonnenburg@stanford.edu.

Funding

TRAINING GRANT IN ACADEMIC GASTROENTEROLOGYT32DK007056 · NIDDK · STANFORD UNIVERSITY · PI Natalie J. Torok · 1986 to 2026
$6.5M
Impact of Diet on Intestinal Microbiota-Host DynamicsR01DK085025 · NIDDK · STANFORD UNIVERSITY · PI JUSTIN L SONNENBURG · 2010 to 2026
$6.4M
NIDDK NIH HHS R01 DK085025NIDDK NIH HHS T32 DK007056
6 · The paper itself

Abstract

Ha and colleagues describe a previously unappreciated diversity of microbes in the mesenteric adipose tissue (MAT) surrounding the GI tract. Viable bacteria that are mislocalized from the gut microbiota and metabolically adapted to the MAT contribute to the "creeping fat" of Crohn's disease.

Indexed as

Crohn DiseaseGastrointestinal MicrobiomeAdaptation, PhysiologicalAdipose TissueHumansMesentery

Identifiers

PMID33125887
PMCPMC8101628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.