ReviewChemistry (Weinheim an der Bergstrasse, Germany)2021
Isoindolinone Synthesis via One-Pot Type Transition Metal Catalyzed C-C Bond Forming Reactions.
Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 79 citations in OpenAlex.
- Upcycling Silicon as Heterogeneous Palladium Catalysts: Heck-Cassar Cross-Coupling in Batch and Flow Conditions.ChemSusChem · 2026Article
- One-Pot Tandem Construction of Isoindolinone Derivatives under Visible-Light Photoredox Catalysis.ACS omega · 2026Article
- Article
- Tetrabutylammonium decatungstate-catalyzed hydroalkylation/alkoxylation of 3-methyleneisoindolin-1-ones with alcohols/ethers through hydrogen atom transfer process.RSC advances · 2025Article
- Multi-Component Synthesis of New Fluorinated-Pyrrolo[3,4-International journal of molecular sciences · 2025Article
- Atroposelective [4+1] annulation for the synthesis of isotopic isoindolinones bearing both central and axial chirality.Chemical science · 2025Article
- Synthesis of 3,3-Disubstituted Allyl Isoindolinones via Pd-Catalyzed Decarboxylative Allylic Alkylation.Tetrahedron letters · 2024Article
- Exploring isoindolin-1-ones as potential CDK7 inhibitors using cheminformatic tools.In silico pharmacology · 2024Article
- Novel Oleanolic Acid-Phtalimidines Tethered 1,2,3 Triazole Hybrids as Promising Antibacterial Agents: Design, Synthesis, In Vitro Experiments and In Silico Docking Studies.Molecules (Basel, Switzerland) · 2023Article
- Asymmetric Cascade Aza-Henry/Lactamization Reaction in the Highly Enantioselective Organocatalytic Synthesis of 3-(Nitromethyl)isoindolin-1-ones from α-Amido Sulfones.The Journal of organic chemistry · 2022Article
- Base-Promoted Cascade Reactions for the Synthesis of 3,3-Dialkylated Isoindolin-1-ones and 3-Methyleneisoindolin-1-ones.The Journal of organic chemistry · 2021Article
- Article
- Isoindolinone Synthesis via One-Pot Type Transition Metal Catalyzed C-C Bond Forming Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Isoindolinone structure is an important privileged scaffold found in a large variety of naturally occurring as well as synthetic, biologically and pharmaceutically active compounds. Owing to its crucial role in a number of applications, the synthetic methodologies for accessing this heterocyclic skeleton have received significant attention during the past decade. In general, the synthetic strategies can be divided into two categories: First, direct utilization of phthalimides or phthalimidines as starting materials for the synthesis of isoindolinones; and second, construction of the lactam and/or aromatic rings by different catalytic methods, including C-H activation, cross-coupling, carbonylation, condensation, addition and formal cycloaddition reactions. Especially in the last mentioned, utilization of transition metal catalysts provides access to a broad range of substituted isoindolinones. Herein, the recent advances (2010-2020) in transition metal catalyzed synthetic methodologies via formation of new C-C bonds for isoindolinones are reviewed.
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