Evidence map›Paper›PMID 33125788›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Circulating mitochondrial genes detect acute cardiac allograft rejection: Role of the mitochondrial calcium uniporter complex.

Estefanía Tarazón, Lorena Pérez-Carrillo, Pau García-Bolufer, Juan C Triviño, Sandra Feijóo-Bandín, Francisca Lago, José R González-Juanatey, Luis Martínez-Dolz, Manuel Portolés, Esther Roselló-Lletí

Open access · greenAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Transcriptomics in transplantation: More than just biomarkers of allograft rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Estefanía TarazónMyocardial Dysfunction and Cardiac Transplantation Unit, Health Research Institute Hospital La Fe (IIS La Fe, Valencia, Spain.
Lorena Pérez-CarrilloMyocardial Dysfunction and Cardiac Transplantation Unit, Health Research Institute Hospital La Fe (IIS La Fe, Valencia, Spain.
Pau García-BoluferMyocardial Dysfunction and Cardiac Transplantation Unit, Health Research Institute Hospital La Fe (IIS La Fe, Valencia, Spain.
Juan C TriviñoGenomic Systems, Paterna, Valencia, Spain.
Sandra Feijóo-BandínCIBERCV, Madrid, Spain.
Francisca LagoCIBERCV, Madrid, Spain.
José R González-JuanateyCIBERCV, Madrid, Spain.
Luis Martínez-DolzMyocardial Dysfunction and Cardiac Transplantation Unit, Health Research Institute Hospital La Fe (IIS La Fe, Valencia, Spain.
Manuel PortolésMyocardial Dysfunction and Cardiac Transplantation Unit, Health Research Institute Hospital La Fe (IIS La Fe, Valencia, Spain.
Esther Roselló-LletíMyocardial Dysfunction and Cardiac Transplantation Unit, Health Research Institute Hospital La Fe (IIS La Fe, Valencia, Spain.ORCID 0000-0003-2627-6104
Centro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital Universitari i Politècnic La Fe · ESSistemas Genómicos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute rejection after heart transplantation increases the risk of chronic dysfunction. Disturbances in mitochondrial function may play a contributory role, however, the relationship between histological signs of rejection in the human transplanted heart and expression levels of circulating mitochondrial genes, such as the mitochondrial Ca

Indexed as

CalciumCation Transport ProteinsAllograftsCalcium-Binding ProteinsCalcium ChannelsGenes, MitochondrialHumansMitochondrial Membrane Transport ProteinsCalciumCalcium-Binding ProteinsCalcium ChannelsCation Transport ProteinsMICU1 protein, humanmitochondrial calcium uniporterMitochondrial Membrane Transport Proteinsbiomarkercell death: apoptosisgenomicsheart biologyheart transplantation/cardiologymolecular biologyrejection: acutetranslational research/science

Identifiers

PMID33125788
PMCPMC8246899
OpenAlexW3094962191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.