Evidence map›Paper›PMID 33125602›Full record

SynthesisEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2021

Rifampin-accompanied antibiotic regimens in the treatment of prosthetic joint infections: a frequentist and Bayesian meta-analysis of current evidence.

Ozlem Aydın, Pinar Ergen, Burak Ozturan, Korhan Ozkan, Ferhat Arslan, Haluk Vahaboglu

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. If, When, and How to Use Rifampin in Acute Staphylococcal Periprosthetic Joint Infections, a Multicentre Observational Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Observational
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ozlem AydınEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Göztepe Eğitim ve Araştırma Hastanesi, İstanbul Medeniyet Üniversitesi, Dr. Erkin Caddesi, 34722, Kadıköy, Istanbul, Turkey.
Pinar ErgenEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Göztepe Eğitim ve Araştırma Hastanesi, İstanbul Medeniyet Üniversitesi, Dr. Erkin Caddesi, 34722, Kadıköy, Istanbul, Turkey.
Burak OzturanOrtopedi Anabilim Dalı, İstanbul Medeniyet Üniversitesi, Istanbul, Turkey.
Korhan OzkanOrtopedi Anabilim Dalı, İstanbul Medeniyet Üniversitesi, Istanbul, Turkey.
Ferhat ArslanEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Göztepe Eğitim ve Araştırma Hastanesi, İstanbul Medeniyet Üniversitesi, Dr. Erkin Caddesi, 34722, Kadıköy, Istanbul, Turkey.
Haluk VahabogluEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Göztepe Eğitim ve Araştırma Hastanesi, İstanbul Medeniyet Üniversitesi, Dr. Erkin Caddesi, 34722, Kadıköy, Istanbul, Turkey. vahabo@hotmail.com.ORCID http://orcid.org/0000-0001-8217-1767
Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi · TRIstanbul Medeniyet University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prosthetic joint infections cause serious morbidity and mortality among joint arthroplasty patients. Rifampin-accompanied antibiotic regimens are recommended for gram-positive infections. This study aimed to combine current evidence supporting the rifampin supplement to an effective antibiotic in the treatment of prosthetic joint infections. We conducted a random-effects meta-analysis with frequentist and Bayesian approaches. A total of 13 studies, all observational, were included in the final analysis. The predominant bacteria in eight, two, and three studies were Staphylococcus spp., Propionibacterium spp., and Streptococcus spp., respectively. We pooled data from 568 patients in the staphylococcus subset (OR, 1.18; 95% CIs, [0.76; 1.82]; I

Indexed as

Anti-Bacterial AgentsBayes TheoremDrug Therapy, CombinationHumansProsthesis-Related InfectionsRifampinAnti-Bacterial AgentsRifampinArthroplastyPropionibacteriumRifampinStaphylococcusStreptococcus

Identifiers

PMID33125602
OpenAlexW3097159946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.