Evidence map›Paper›PMID 33125000›Full record

ArticleClinical kidney journal2020

Prognostic value for long-term graft survival of estimated glomerular filtration rate and proteinuria quantified at 3 months after kidney transplantation.

Clément Mottola, Nicolas Girerd, Kevin Duarte, Alice Aarnink, Magali Giral, Jacques Dantal, Valérie Garrigue, Georges Mourad, Fanny Buron, Emmanuel Morelon and 5 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 1 country.

Clément MottolaDepartment of Nephrology and Kidney Transplantation, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Nicolas GirerdINSERM U1116, Clinical Investigation Centre, Lorraine University, Vandoeuvre-lès-Nancy, France.
Kevin DuarteINSERM U1116, Clinical Investigation Centre, Lorraine University, Vandoeuvre-lès-Nancy, France.
Alice AarninkDepartment of Immunology and Histocompatibility, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Magali GiralCRTI UMR 1064, Inserm, Nantes University, Nantes, France.
Jacques DantalCRTI UMR 1064, Inserm, Nantes University, Nantes, France.
Valérie GarrigueDepartment of Nephrology and Kidney Transplantation, Montpellier University Hospital, Montpellier, France.
Georges MouradDepartment of Nephrology and Kidney Transplantation, Montpellier University Hospital, Montpellier, France.
Fanny BuronDepartment of Nephrology and Kidney Transplantation, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.
Emmanuel MorelonDepartment of Nephrology and Kidney Transplantation, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.
Marc LadrièreDepartment of Nephrology and Kidney Transplantation, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Michèle KesslerDepartment of Nephrology and Kidney Transplantation, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Luc FrimatDepartment of Nephrology and Kidney Transplantation, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Sophie GirerdDepartment of Nephrology and Kidney Transplantation, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
DIVAT Consortium
French Clinical Research Infrastructure Network · FRHôpital Lapeyronie · FRCentre Hospitalier Régional et Universitaire de Nancy · FRHospices Civils de Lyon · FRInserm · FRNantes Université · FRUniversité de Montpellier · FRCenter for Research in Transplantation and Translational ImmunologyCentre Hospitalier Universitaire de Montpellier · FRDéfaillance Cardiovasculaire Aiguë et ChroniqueInstitut de Transplantation Urologie en Nephrologie · FRUniversité de Lorraine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe estimated glomerular filtration rate (eGFR) measured at 1 year is the usual benchmark applied in kidney transplantation (KT). However, acting on earlier eGFR values could help in managing KT during the first post-operative year. We aimed to assess the prognostic value for long-term graft survival of the early (3 months) quantification of eGFR and proteinuria following KT.

methodsThe 3-, 6- and 12-month eGFR using the Modified Diet in Renal Disease equation (eGFR

resultsBoth 3-month eGFR

conclusionThe 3-month eGFR was a valuable predictor of the long-term return to dialysis whose predictive accuracy was not significantly less than that of the 12-month eGFR in multicentre cohorts totalling >2500 patients. Three-month outcomes may be useful in randomized controlled trials targeting early therapeutic interventions.

Indexed as

creatininedelayed graft functiongraft survivalischaemia reperfusion injurykidney transplantationproteinuria

Identifiers

PMID33125000
PMCPMC7577768
OpenAlexW3020022355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.