Evidence map›Paper›PMID 33124981›Full record

ArticleeLife2020

A low affinity

Anthony Je Berndt, Katerina M Othonos, Tianshun Lian, Stephane Flibotte, Mo Miao, Shamsuddin A Bhuiyan, Raymond Y Cho, Justin S Fong, Seo Am Hur, Paul Pavlidis and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Dysregulation of BMP, Wnt, and Insulin Signaling in Fragile X Syndrome.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Anthony Je Berndt *Department of Food & Fuel for the 21st Century, University of California San Diego, San Diego, United States.ORCID 0000-0002-0132-7393
Katerina M Othonos *Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Tianshun LianDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Stephane FlibotteUBC/LSI Bioinformatics Facility, University of British Columbia, Vancouver, Canada.
Mo MiaoDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Shamsuddin A BhuiyanDepartment of Psychiatry, University of British Columbia, Vancouver, Canada.
Raymond Y ChoDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Justin S FongDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.
Seo Am HurDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.ORCID 0000-0003-4163-7182
Paul PavlidisDepartment of Psychiatry, University of British Columbia, Vancouver, Canada.ORCID 0000-0002-0426-5028
Douglas W AllanDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.ORCID 0000-0002-3488-8365
University of British Columbia · CAUniversity of California San Diego · US

Funding

CIHR MOP-130517CIHR MOP-98011
6 · The paper itself

Abstract

Retrograde BMP signaling and canonical pMad/Medea-mediated transcription regulate diverse target genes across subsets of

Indexed as

Response ElementsAnimalsBone Morphogenetic ProteinsDrosophila melanogasterDrosophila ProteinsGene Expression RegulationNeuronsSignal TransductionSmad4 ProteinBone Morphogenetic ProteinsDrosophila ProteinsMed protein, DrosophilaSmad4 Proteinbmp-activated smad transcription factorscis-regulatory bmp response elementD. melanogasterlow affinity binding motifneuroscience

Identifiers

PMID33124981
PMCPMC7669266
OpenAlexW3095081094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.